Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9102487 | 0.89 | HRH3 (0.68) | HRH3KCNH2 | |
| SCHEMBL9105336 | 0.83 | HRH3 (0.71) | HRH3KCNH2 | |
| SCHEMBL1574398 | 0.81 | KCNH2 (1.00) | HRH3KCNH2 | |
| SCHEMBL9106427 | 0.81 | HRH3 (0.49) | HRH3KCNH2 | |
| SCHEMBL9105452 | 0.79 | HRH3 (0.72) | HRH3KCNH2 | |
| SCHEMBL9104708 | 0.78 | HRH3 (0.43) | HRH3KCNH2 | |
| SCHEMBL9103690 | 0.75 | HRH3 (0.50) | HRH3KCNH2 | |
| SCHEMBL9105288 | 0.75 | HRH3 (0.57) | HRH3KCNH2 | |
| SCHEMBL9103647 | 0.75 | HRH3 (0.68) | HRH3KCNH2 | |
| SCHEMBL9105842 | 0.74 | HRH3 (0.52) | HRH3KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1751149-B1 | BICYCLIC-SUBSTITUTED AMINES HAVING CYCLIC-SUBSTITUTED MONOCYCLIC SUBSTITUENTS | ABBOTT LAB (US) | 2012-06-06 | — | — | EP | claimed |