SCHEMBL9104546

SCHEMBL9104546

CCCc1ccc2c(c1)Sc1ccccc1N2CCCS(=O)(=O)O

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 4/20 0.51
KMT2A Q03164 4/20 0.51
MAPT P10636 4/20 0.51
POLB P06746 2/20 0.51
MMP13 P45452 2/20 0.51
ALOX15 P16050 3/20 0.49
KDM4E B2RXH2 3/20 0.49
TP53 P04637 3/20 0.49
TDP1 Q9NUW8 2/20 0.49
RAD52 P43351 2/20 0.49
L3MBTL1 Q9Y468 2/20 0.49
USP2 O75604 1/20 0.49
CYP3A4 P08684 1/20 0.49
MAPK1 P28482 1/20 0.49
HPGD P15428 3/20 0.47
HSD17B10 Q99714 3/20 0.47
ALOX12 P18054 2/20 0.47
CASP1 P29466 2/20 0.47
ALDH1A1 P00352 2/20 0.47
LMNA P02545 2/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9102733 0.94 MEN1 (0.50) MEN1KMT2AMAPTPOLBMMP13
SCHEMBL9100574 0.93 MAPT (0.54) MEN1KMT2AMAPTPOLBMMP13
SCHEMBL9100359 0.92 MAPT (0.45) MEN1KMT2AMAPTPOLBMMP13
SCHEMBL9102609 0.91 MEN1 (0.53) MEN1KMT2AMAPTPOLBMMP13
SCHEMBL9105725 0.88 MAPT (0.53) MEN1KMT2AMAPTPOLBMMP13
SCHEMBL9101693 0.86 MAPT (0.45) MEN1KMT2AMAPTPOLBMMP13
SCHEMBL9104972 0.86 MEN1 (0.41) MEN1KMT2AMAPTPOLBMMP13
SCHEMBL9100805 0.85 MEN1 (0.48) MEN1KMT2AMAPTPOLBMMP13
SCHEMBL30115198 0.84 MEN1 (0.58) MEN1KMT2AMAPTPOLBMMP13
SCHEMBL30115197 0.84 MEN1 (0.58) MEN1KMT2AMAPTPOLBMMP13

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8192948-B1 Chemifluorescent substrate for peroxide and peroxidase detection PIERCE BIOTECHNOLOGY, INC. (US) 2012-06-05 US disclosed
EP-0361470-B1 Method for the chemiluminescence assay of the activity of peroxidase FUJIREBIO KK (JP) 1993-12-22 EP disclosed
US-5171668-A Measuring light emitted from contacting (iso)luminol, peroxide, peroxidase activity enhancer, such as indoanilines, phenolindophenol and N-methylphenothiazine, with labeled peroxidase antibody-antigen complex FUJIREBIO INC. (JP) 1992-12-15 US disclosed
EP-0361470-A2 Method for the chemiluminescence assay of the activity of peroxidase FUJIREBIO INC. (JP) 1990-04-04 EP disclosed