SCHEMBL9104571

SCHEMBL9104571

CCCc1cccc2c1Sc1ccccc1N2CCCS(=O)(=O)O

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 6/20 0.51
MEN1 O00255 5/20 0.51
KMT2A Q03164 5/20 0.51
POLB P06746 4/20 0.51
MMP13 P45452 3/20 0.51
ALOX15 P16050 4/20 0.47
HPGD P15428 4/20 0.47
ALDH1A1 P00352 4/20 0.47
ALOX12 P18054 3/20 0.47
CASP1 P29466 3/20 0.47
HSD17B10 Q99714 3/20 0.47
TDP1 Q9NUW8 3/20 0.47
CASP7 P55210 2/20 0.47
LMNA P02545 2/20 0.47
PKM P14618 1/20 0.47
CTDSP1 Q9GZU7 2/20 0.46
RXFP1 Q9HBX9 1/20 0.46
L3MBTL1 Q9Y468 3/20 0.45
KDM4E B2RXH2 3/20 0.45
TP53 P04637 2/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9106145 0.94 MAPT (0.50) MAPTMEN1KMT2APOLBMMP13
SCHEMBL9103398 0.92 MEN1 (0.53) MAPTMEN1KMT2APOLBMMP13
SCHEMBL9104784 0.90 MAPT (0.43) MAPTMEN1KMT2APOLBMMP13
SCHEMBL9104972 0.88 MEN1 (0.41) MAPTMEN1KMT2APOLBMMP13
SCHEMBL9101923 0.87 MEN1 (0.48) MAPTMEN1KMT2APOLBMMP13
SCHEMBL9105207 0.86 MAPT (0.51) MAPTMEN1KMT2APOLBMMP13
SCHEMBL9102136 0.84 MAPT (0.42) MAPTMEN1KMT2APOLBMMP13
SCHEMBL9100972 0.83 MEN1 (0.52) MAPTMEN1KMT2APOLBMMP13
SCHEMBL9105694 0.83 MEN1 (0.52) MAPTMEN1KMT2APOLBMMP13
SCHEMBL9099252 0.83 MAPT (0.38) MAPTMEN1KMT2APOLBMMP13

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8192948-B1 Chemifluorescent substrate for peroxide and peroxidase detection PIERCE BIOTECHNOLOGY, INC. (US) 2012-06-05 US disclosed
EP-0361470-B1 Method for the chemiluminescence assay of the activity of peroxidase FUJIREBIO KK (JP) 1993-12-22 EP disclosed
US-5171668-A Measuring light emitted from contacting (iso)luminol, peroxide, peroxidase activity enhancer, such as indoanilines, phenolindophenol and N-methylphenothiazine, with labeled peroxidase antibody-antigen complex FUJIREBIO INC. (JP) 1992-12-15 US disclosed
EP-0361470-A2 Method for the chemiluminescence assay of the activity of peroxidase FUJIREBIO INC. (JP) 1990-04-04 EP disclosed