SCHEMBL910458

SCHEMBL910458

C=C/C=C/[C]=O

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL910459 1.00
SCHEMBL8159206 0.87
SCHEMBL8159203 0.87
SCHEMBL14861053 0.76
SCHEMBL6365838 0.67
SCHEMBL834791 0.67
SCHEMBL6365840 0.67
SCHEMBL834790 0.67
SCHEMBL79832 0.66
SCHEMBL9207872 0.66

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 73 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114432327-A Application of flavonoid carbon glycoside compound in preparation of medicine for preventing or treating acute lung injury and/or acute respiratory distress syndrome 苏州凯祥生物科技有限公司 2022-05-06 CN claimed
CN-106795174-B Antiviral active diazacyclospirodiketopiperazine alkaloid derivative and preparation method thereof 扬州蓝色生物医药科技有限公司 2020-04-28 CN claimed
EP-3108900-B1 PROTOTYPE SYSTEMS OF THERANOSTIC BIOMARKERS FOR IN VIVO MOLECULAR MANAGEMENT OF CANCER EPOS IASIS RES AND DEVELOPMENT LTD (CY) 2019-04-24 EP claimed
US-9890187-B2 Prototype systems of theranostic biomarkers for in vivo molecular management of cancer EPOS-IASIS RESEARCH AND DEVELOPMENT, LTD. (CY) 2018-02-13 US claimed
US-6110933-A AN ENZYME INHIBITOR TREATING PANCREATITIS, HEPATITIS, CHRONIC RENAL FAILURE, ENDOTOXIN SHOCK, GRAM-NEGATIVE SEPTIC SHOCK, ARTHRITIS, RESPIRATORY DISEASE, HEART DISEASE, ALLERGIC DISEASE, THROMBOSIS, ARTERIOSCLEROSIS, PAIN FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 2000-08-29 US claimed
JP-9059139-A None JP disclosed
EP-3741865-B1 NON-NATURAL MICROBIAL ORGANISMS WITH IMPROVED ENERGETIC EFFICIENCY GENOMATICA INC (US) 2024-03-13 EP disclosed
CN-111825631-B BE-43547 derivative and salt thereof, preparation method and application thereof in preparation of anticancer drugs 新沂尚德药缘药业有限公司 2023-10-13 CN disclosed
US-20230287464-A1 MICROORGANISMS AND METHODS FOR THE PRODUCTION OF BUTADIENE USING ACETYL-COA GENOMATICA INC (US) 2023-09-14 US disclosed
US-20230126921-A1 NON-NATURAL MICROBIAL ORGANISMS WITH IMPROVED ENERGETIC EFFICIENCY AGAIN BIO APS (DK) 2023-04-27 US disclosed
US-11371063-B2 Microorganisms and methods for the production of butadiene using acetyl-coA GENOMATICA, INC. (US) 2022-06-28 US disclosed
CN-114432327-A Application of flavonoid carbon glycoside compound in preparation of medicine for preventing or treating acute lung injury and/or acute respiratory distress syndrome 苏州凯祥生物科技有限公司 2022-05-06 CN disclosed
EP-0906115-A1 COMBINED USE OF GnRH AGONIST AND ANTAGONIST Takeda Chemical Industries, Ltd. (JP) 1999-04-07 EP disclosed
EP-0854863-A1 ESTERS AND AMIDES AS PLA2 INHIBITORS FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1998-07-29 EP disclosed
WO-1997040846-A1 COMBINED USE OF GnRH AGONIST AND ANTAGONIST TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1997-11-06 WO disclosed
EP-0781774-A2 Prolactin production inhibitory agents TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1997-07-02 EP disclosed
JP-H0959139-A PENTADIENOYL DERIVATIVE AND ULTRAVIOLET RAY ABSORBER NISSIN FOOD PROD CO LTD 1997-03-04 JP disclosed
WO-1997003951-A1 ESTERS AND AMIDES AS PLA2 INHIBITORS FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1997-02-06 WO disclosed
EP-0741697-A1 AMINO ACID DERIVATIVES AND THEIR USE AS PHOSPHOLIPASE A2 INHIBITORS FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1996-11-13 EP disclosed
WO-1995019959-A1 AMINO ACID DERIVATIVES AND THEIR USE AS PHOSPHOLIPASE A2 INHIBITORS FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1995-07-27 WO disclosed