Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 20/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1310925 | 0.92 | MAPK14 (0.85) | MAPK14 | |
| SCHEMBL1311225 | 0.88 | MAPK14 (1.00) | MAPK14 | |
| SCHEMBL1310604 | 0.86 | MAPK14 (1.00) | MAPK14 | |
| SCHEMBL1312373 | 0.86 | MAPK14 (0.79) | MAPK14 | |
| SCHEMBL1311772 | 0.85 | MAPK14 (1.00) | MAPK14 | |
| SCHEMBL1310858 | 0.85 | MAPK14 (0.80) | MAPK14 | |
| SCHEMBL1311202 | 0.84 | MAPK14 (0.79) | MAPK14 | |
| SCHEMBL1312162 | 0.83 | MAPK14 (0.77) | MAPK14 | |
| SCHEMBL1311301 | 0.82 | MAPK14 (0.75) | MAPK14 | |
| SCHEMBL1311191 | 0.82 | MAPK14 (0.75) | MAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2334674-B1 | Pyridazino- pyridinone compounds for the treatment of protein kinase mediated diseases. | AMGEN INC (US) | 2012-06-06 | — | — | EP | disclosed |