SCHEMBL9105518

SCHEMBL9105518

Cc1cccc2c1N(CCCS(=O)(=O)O)c1ccccc1S2

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 6/20 0.52
KMT2A Q03164 6/20 0.52
MAPT P10636 6/20 0.52
POLB P06746 4/20 0.52
MMP13 P45452 3/20 0.52
ALOX15 P16050 4/20 0.48
HPGD P15428 4/20 0.48
ALDH1A1 P00352 4/20 0.48
ALOX12 P18054 3/20 0.48
CASP1 P29466 3/20 0.48
HSD17B10 Q99714 3/20 0.48
TDP1 Q9NUW8 3/20 0.48
LMNA P02545 3/20 0.48
CASP7 P55210 2/20 0.48
PKM P14618 1/20 0.48
KDM4E B2RXH2 3/20 0.47
L3MBTL1 Q9Y468 3/20 0.47
TP53 P04637 2/20 0.47
MAPK1 P28482 2/20 0.47
USP2 O75604 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9102553 0.89 MAPT (0.43) MEN1KMT2AMAPTPOLBMMP13
SCHEMBL9105620 0.88 MAPT (0.45) MEN1KMT2AMAPTPOLBMMP13
SCHEMBL9104960 0.87 MAPT (0.49) MEN1KMT2AMAPTPOLBMMP13
SCHEMBL9100529 0.86 MEN1 (0.53) MEN1KMT2AMAPTPOLBMMP13
SCHEMBL30115197 0.85 MEN1 (0.58) MEN1KMT2AMAPTPOLBMMP13
SCHEMBL30115198 0.85 MEN1 (0.58) MEN1KMT2AMAPTPOLBMMP13
SCHEMBL48681 0.85 MEN1 (0.58) MEN1KMT2AMAPTPOLBMMP13
SCHEMBL9100585 0.85 HDAC1 (0.51) MEN1KMT2AMAPTPOLBMMP13
SCHEMBL9102822 0.85 MEN1 (0.49) MEN1KMT2AMAPTPOLBMMP13
SCHEMBL9100972 0.85 MEN1 (0.52) MEN1KMT2AMAPTPOLBMMP13

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8192948-B1 Chemifluorescent substrate for peroxide and peroxidase detection PIERCE BIOTECHNOLOGY, INC. (US) 2012-06-05 US disclosed
EP-0361470-B1 Method for the chemiluminescence assay of the activity of peroxidase FUJIREBIO KK (JP) 1993-12-22 EP disclosed
US-5171668-A Measuring light emitted from contacting (iso)luminol, peroxide, peroxidase activity enhancer, such as indoanilines, phenolindophenol and N-methylphenothiazine, with labeled peroxidase antibody-antigen complex FUJIREBIO INC. (JP) 1992-12-15 US disclosed
EP-0361470-A2 Method for the chemiluminescence assay of the activity of peroxidase FUJIREBIO INC. (JP) 1990-04-04 EP disclosed