SCHEMBL9107098

SCHEMBL9107098

NCCOc1cccc(OCCN)c1

nearest known ligand 0.70

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 1/20 0.70
LTA4H P09960 2/20 0.59
PLA2G2A P14555 1/20 0.59
KDM4E B2RXH2 1/20 0.50
ROCK2 O75116 1/20 0.49
PRKACA P17612 1/20 0.49
PRKCD Q05655 1/20 0.49
ROCK1 Q13464 1/20 0.49
DYRK1A Q13627 1/20 0.49
CDC42BPA Q5VT25 1/20 0.49
PRSS1 P07477 6/20 0.47
MAPK1 P28482 1/20 0.46
TSHR P16473 1/20 0.46
HTR1B P28222 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31447135 0.89 MAPK1 (0.61) TAAR1MAPK1TSHR
SCHEMBL4542738 0.89 MAPK1 (0.61) TAAR1MAPK1TSHR
SCHEMBL10848210 0.89 TP53 (0.60) TAAR1LTA4HPLA2G2AKDM4EMAPK1
SCHEMBL2206757 0.89 TAAR1 (0.57) TAAR1LTA4HPLA2G2AROCK2PRKACA
SCHEMBL4569115 0.89 TAAR1 (0.57) TAAR1LTA4HPLA2G2AKDM4EMAPK1
SCHEMBL19291701 0.88 TSHR (0.59) TAAR1LTA4HPLA2G2ATSHR
SCHEMBL29819073 0.88 TAAR1 (0.55) TAAR1LTA4HPLA2G2AKDM4EROCK2
SCHEMBL2204148 0.88 TAAR1 (0.55) TAAR1LTA4HPLA2G2AKDM4EROCK2
SCHEMBL2205073 0.88 TAAR1 (0.55) TAAR1LTA4HPLA2G2AROCK2PRKACA
SCHEMBL29818959 0.88 TAAR1 (0.55) TAAR1LTA4HPLA2G2AROCK2PRKACA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2020203818-A1 ASBESTOS DETECTING AGENT, ASBESTOS DETECTING KIT, AND ASBESTOS DETECTING METHOD 広島県 2020-10-08 WO disclosed
EP-2670375-B1 DENTAL COMPOSITION, METHOD OF PRODUCING AND USE THEREOF 3M INNOVATIVE PROPERTIES CO (US) 2019-05-01 EP disclosed
US-20120141398-A1 HAIR DYE CONTAINING ONE OR MORE EDIBLE OR COSMETIC COLORS CHUANG KUO SHENG (TW) 2012-06-07 US disclosed
US-4323360-A Dyeing compositions for hair which contain 2,4-diamino-butoxybenzene and/or a salt thereof as the coupling agent L'OREAL (FR) 1982-04-06 US disclosed