SCHEMBL91077

SCHEMBL91077

CCCCCC(=O)NC(CCC(=O)NCCOCC)C(=O)O

nearest known ligand 0.66

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
GLP1R P43220 8/20 0.66
NOD1 Q9Y239 11/20 0.64
SLC6A5 Q9Y345 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15002885 0.99 GLP1R (0.67) GLP1RNOD1SLC6A5
SCHEMBL24788081 0.99 GLP1R (0.67) GLP1RNOD1SLC6A5
SCHEMBL26859325 0.99 GLP1R (0.67) GLP1RNOD1SLC6A5
SCHEMBL13640904 0.99 GLP1R (0.67) GLP1RNOD1SLC6A5
SCHEMBL13640857 0.96 GLP1R (0.71) GLP1RNOD1SLC6A5
SCHEMBL13025155 0.96 GLP1R (0.71) GLP1RNOD1SLC6A5
SCHEMBL15002884 0.96 GLP1R (0.71) GLP1RNOD1SLC6A5
SCHEMBL24795598 0.96 GLP1R (0.71) GLP1RNOD1SLC6A5
SCHEMBL13640952 0.96 GLP1R (0.71) GLP1RNOD1SLC6A5
SCHEMBL24796092 0.96 GLP1R (0.71) GLP1RNOD1SLC6A5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8129343-B2 Acylated GLP-1 compounds NOVO NORDISK A/S (DK) 2012-03-06 US disclosed