SCHEMBL9109727

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL9109083	0.94	MAPKAPK5 (0.61)	MAPKAPK5MAPKAPK2NMT1MAPK14MAPK1
	SCHEMBL9109604	0.94	MAPKAPK2 (0.53)	MAPKAPK5MAPKAPK2NMT1MAPK14MAPK1
	SCHEMBL9110161	0.92	MAPKAPK5 (0.54)	MAPKAPK5MAPKAPK2NMT1MAPK14MAPK1
	SCHEMBL9110981	0.92	MAPKAPK5 (0.60)	MAPKAPK5MAPKAPK2MAPK14MAPK1
	SCHEMBL9112252	0.89	MAPKAPK5 (0.46)	MAPKAPK5MAPKAPK2MAPK14MAPK1HTR2A
	SCHEMBL9109972	0.88	MAPKAPK5 (0.56)	MAPKAPK5MAPKAPK2MAPK14MAPK1
	SCHEMBL9111195	0.88	MAPKAPK5 (0.70)	MAPKAPK5MAPKAPK2MAPK14MAPK1
	SCHEMBL9109896	0.88	MAPKAPK2 (0.60)	MAPKAPK5MAPKAPK2NMT1MAPK14MAPK1
	SCHEMBL9111476	0.87	MAPKAPK5 (0.56)	MAPKAPK5MAPKAPK2MAPK14MAPK1
	SCHEMBL9110848	0.86	MAPKAPK2 (0.45)	MAPKAPK5MAPKAPK2NMT1MAPK14HTR2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.