SCHEMBL9109731

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL9110772	0.94	MAPKAPK2 (0.44)	MAPKAPK2MAPKAPK5MAPTHTTSMN1; SMN2
	SCHEMBL9110765	0.92	MAPK14 (0.46)	MAPKAPK2MAPKAPK5MAPTHTTSMN1; SMN2
	SCHEMBL9110429	0.92	MAPKAPK2 (0.42)	MAPKAPK2MAPKAPK5MAPTHTTSMN1; SMN2
	SCHEMBL9110336	0.91	MAPKAPK2 (0.40)	MAPKAPK2MAPKAPK5HTTMAPK14MAOB
	SCHEMBL9109961	0.90	MAPT (0.35)	MAPKAPK2MAPKAPK5MAPTHTTSMN1; SMN2
	SCHEMBL9109426	0.88	MAPKAPK2 (0.51)	MAPKAPK2MAPKAPK5MAPTHTTSMN1; SMN2
	SCHEMBL9111376	0.88	MAPKAPK2 (0.52)	MAPKAPK2MAPKAPK5MAPTHTTSMN1; SMN2
	SCHEMBL9111005	0.86	SMN1; SMN2 (0.39)	MAPTHTTSMN1; SMN2MAPK14MAOB
	SCHEMBL9109756	0.86	MAPKAPK5 (0.54)	MAPKAPK2MAPKAPK5MAPTHTTSMN1; SMN2
	SCHEMBL9110325	0.86	MAPKAPK2 (0.39)	MAPKAPK2MAPKAPK5MAPK14

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.