Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B7 | P56937 | 2/20 | 0.44 |
| ▸ | SRD5A1 | P18405 | 12/20 | 0.43 |
| ▸ | SRD5A2 | P31213 | 5/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8679325 | 0.85 | SRD5A1 (0.34) | HSD17B7SRD5A1SRD5A2 | |
| SCHEMBL8679334 | 0.80 | SRD5A1 (0.33) | HSD17B7SRD5A1SRD5A2 | |
| SCHEMBL9005677 | 0.78 | SRD5A1 (0.56) | SRD5A1SRD5A2 | |
| SCHEMBL9005680 | 0.78 | SRD5A1 (0.56) | SRD5A1SRD5A2 | |
| SCHEMBL5069369 | 0.77 | SRD5A1 (0.43) | SRD5A1SRD5A2 | |
| SCHEMBL5069375 | 0.77 | SRD5A1 (0.43) | SRD5A1SRD5A2 | |
| SCHEMBL8682901 | 0.76 | SRD5A1 (0.35) | SRD5A1SRD5A2 | |
| SCHEMBL9546838 | 0.75 | SRD5A1 (0.41) | SRD5A1SRD5A2 | |
| SCHEMBL9115003 | 0.75 | SRD5A1 (0.41) | SRD5A1SRD5A2 | |
| SCHEMBL8606544 | 0.74 | SRD5A1 (0.35) | SRD5A1SRD5A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0641204-A4 | 17-ETHERS AND THIOETHERS OF 4-AZA-STEROIDS. | MERCK & CO INC (US) | 1995-08-23 | — | — | EP | disclosed |
| EP-0641204-A1 | 17-ETHERS AND THIOETHERS OF 4-AZA-STEROIDS | MERCK & CO. INC. (US) | 1995-03-08 | — | — | EP | disclosed |