Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYMS | P04818 | 5/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | BCHE | P06276 | 1/20 | 0.32 |
| ▸ | PTPRC | P08575 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | IDO1 | P14902 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | CES1 | P23141 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL148025 | 0.84 | TYMS (0.62) | TYMSALOX15TDP1ALDH1A1MEN1 | |
| SCHEMBL20832212 | 0.77 | TYMS (0.37) | TYMSALOX15TDP1 | |
| SCHEMBL29349446 | 0.75 | TYMS (0.52) | TYMSALOX15TDP1ALDH1A1MEN1 | |
| SCHEMBL15119575 | 0.75 | TDP1 (0.65) | TYMSALOX15TDP1ALDH1A1MEN1 | |
| SCHEMBL13009255 | 0.75 | TYMS (0.52) | TYMSALOX15TDP1ALDH1A1MEN1 | |
| SCHEMBL30606666 | 0.75 | TYMS (0.52) | TYMSALOX15TDP1ALDH1A1MEN1 | |
| SCHEMBL31185814 | 0.75 | TYMS (0.52) | TYMSALOX15TDP1ALDH1A1MEN1 | |
| SCHEMBL36626 | 0.75 | TYMS (0.52) | TYMSALOX15TDP1ALDH1A1MEN1 | |
| SCHEMBL6388474 | 0.75 | TYMS (0.34) | TYMS | |
| SCHEMBL9111658 | 0.73 | TYMS (0.50) | TYMSALOX15TDP1ALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023054126-A1 | ACTINIC RAY-SENSITIVE OR RADIATION-SENSITIVE RESIN COMPOSITION, ACTINIC RAY-SENSITIVE OR RADIATION-SENSITIVE FILM, PATTERN-FORMING METHOD AND ELECTRONIC DEVICE MANUFACTURING METHOD | 富士フイルム株式会社 | 2023-04-06 | — | — | WO | disclosed |
| EP-0683768-A1 | UNSYMMETRICAL BIS-IMIDES AS ANTICANCER AGENTS | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1995-11-29 | — | — | EP | disclosed |
| WO-1995008539-A1 | IMPROVED METHODS FOR PREPARING BIS-IMIDE COMPOUNDS | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1995-03-30 | — | — | WO | disclosed |
| US-5359070-A | ANTITUMOR AGENTS | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1994-10-25 | — | — | US | disclosed |
| WO-1994018171-A1 | UNSYMMETRICAL BIS-IMIDES AS ANTICANCER AGENTS | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1994-08-18 | — | — | WO | disclosed |