⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28385288 | 0.89 | — | — | |
| SCHEMBL3079746 | 0.73 | — | — | |
| SCHEMBL23200435 | 0.69 | — | — | |
| SCHEMBL1937749 | 0.69 | — | — | |
| SCHEMBL1937416 | 0.69 | — | — | |
| SCHEMBL4337520 | 0.69 | — | — | |
| SCHEMBL592607 | 0.69 | — | — | |
| SCHEMBL7662182 | 0.69 | — | — | |
| SCHEMBL23522571 | 0.69 | — | — | |
| SCHEMBL8935223 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117069726-A | Synthesis method of [1,2-a ] indole polycyclic derivative | 兰州大学 | 2023-11-17 | — | — | CN | claimed |
| EP-2683713-B1 | ISOXAZOLE DERIVATIVES | NOVARTIS TIERGESUNDHEIT AG (CH) | 2015-04-22 | — | — | EP | claimed |
| CN-117069726-A | Synthesis method of [1,2-a ] indole polycyclic derivative | 兰州大学 | 2023-11-17 | — | — | CN | disclosed |
| EP-2683713-B1 | ISOXAZOLE DERIVATIVES | NOVARTIS TIERGESUNDHEIT AG (CH) | 2015-04-22 | — | — | EP | disclosed |
| US-8822466-B2 | Isoxazole derivatives | NOVARTIS AG (CH) | 2014-09-02 | — | — | US | disclosed |
| EP-2683713-A1 | ISOXAZOLE DERIVATIVES | Novartis AG (CH) | 2014-01-15 | — | — | EP | disclosed |
| US-20130345221-A1 | ISOXAZOLE DERIVATIVES | NOVARTIS AG (CH) | 2013-12-26 | — | — | US | disclosed |
| WO-2012120135-A1 | ISOXAZOLE DERIVATIVES | NOVARTIS AG (CH) | 2012-09-13 | — | — | WO | disclosed |
| CN-1114834-A | antidiabetic agent | OTSUKA PHARMA CO LTD (JP) | 1996-01-10 | — | — | CN | disclosed |
| EP-0670831-A1 | QUINOXALINE DERIVATIVE AS ANTIDIABETIC AGENT | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1995-09-13 | — | — | EP | disclosed |
| WO-1995009159-A1 | QUINOXALINE DERIVATIVE AS ANTIDIABETIC AGENT | OTSUKA PHARMACEUTICAL COMPANY, LIMITED (JP) | 1995-04-06 | — | — | WO | disclosed |
| US-4335138-A | HYPNOTIC, SEDATIVE | BASF AKTIENGESELLSCHAFT (DE) | 1982-06-15 | — | — | US | disclosed |
| EP-0026369-A2 | Carbamates, their preparation and pharmaceutical compositions containing them | BASF Aktiengesellschaft (DE) | 1981-04-08 | — | — | EP | disclosed |