SCHEMBL9110395

SCHEMBL9110395

[CH2]CCc1cccc2c1CCC2

nearest known ligand 0.42

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
BCL2L1 Q07817 1/20 0.42
BAD Q92934 1/20 0.42
RXRB P28702 10/20 0.36
RXRA P19793 10/20 0.36
RXRG P48443 7/20 0.36
MRGPRX4 Q96LA9 1/20 0.35
TBXA2R P21731 1/20 0.35
DHFR P00374 2/20 0.35
TSHR P16473 1/20 0.34
ALDH1A1 P00352 1/20 0.34
HTT P42858 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
NPSR1 Q6W5P4 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9115008 0.86 BCL2L1 (0.38) BCL2L1BADRXRBRXRARXRG
SCHEMBL6368014 0.85 BCL2L1 (0.44) BCL2L1BADRXRBRXRARXRG
SCHEMBL231794 0.84 BCL2L1 (0.45) BCL2L1BADRXRBRXRARXRG
SCHEMBL9720039 0.84 BCL2L1 (0.54) BCL2L1BADRXRBRXRARXRG
SCHEMBL9678350 0.81 BCL2L1 (0.42) BCL2L1BADRXRBRXRARXRG
SCHEMBL9070606 0.78 BCL2L1 (0.44) BCL2L1BADRXRBRXRARXRG
SCHEMBL6241252 0.78 DPP4 (0.41) BCL2L1BADTBXA2RALDH1A1
SCHEMBL2099150 0.77 BCL2L1 (0.38) BCL2L1BADRXRBRXRARXRG
SCHEMBL3886272 0.77 BCL2L1 (0.52) BCL2L1BADRXRBRXRARXRG
SCHEMBL8939515 0.77 HTR2A (0.50) BCL2L1BADTBXA2RDHFRTSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1114834-A antidiabetic agent OTSUKA PHARMA CO LTD (JP) 1996-01-10 CN disclosed
EP-0670831-A1 QUINOXALINE DERIVATIVE AS ANTIDIABETIC AGENT OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1995-09-13 EP disclosed
WO-1995009159-A1 QUINOXALINE DERIVATIVE AS ANTIDIABETIC AGENT OTSUKA PHARMACEUTICAL COMPANY, LIMITED (JP) 1995-04-06 WO disclosed