Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KRAS | P01116 | 1/20 | 0.73 |
| ▸ | TNFRSF1A | P19438 | 4/20 | 0.69 |
| ▸ | F3 | P13726 | 2/20 | 0.68 |
| ▸ | CXCL12 | P48061 | 1/20 | 0.66 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.65 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.65 |
| ▸ | MAOB | P27338 | 5/20 | 0.63 |
| ▸ | MAPT | P10636 | 4/20 | 0.63 |
| ▸ | MEN1 | O00255 | 3/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.63 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.63 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.63 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.63 |
| ▸ | MAOA | P21397 | 3/20 | 0.62 |
| ▸ | XDH | P47989 | 2/20 | 0.62 |
| ▸ | P4HB | P07237 | 1/20 | 0.62 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.62 |
| ▸ | RAB9A | P51151 | 1/20 | 0.62 |
| ▸ | NPC1 | O15118 | 2/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9112454 | 0.91 | KRAS (0.64) | KRASTNFRSF1AF3CXCL12MCL1 | |
| SCHEMBL9112835 | 0.89 | MAPT (0.62) | KRASF3ABCG2MAOBMAPT | |
| SCHEMBL9114646 | 0.89 | KRAS (0.62) | KRASTNFRSF1AF3CXCL12MCL1 | |
| SCHEMBL9112514 | 0.89 | MAOB (0.69) | KRASTNFRSF1AF3CXCL12MCL1 | |
| SCHEMBL9113734 | 0.89 | MAPT (0.76) | KRASABCG2MAOBMAPTKMT2A | |
| SCHEMBL9113338 | 0.87 | ABCG2 (0.63) | KRASTNFRSF1AF3ABCG2MAOB | |
| SCHEMBL9114711 | 0.87 | MAOB (0.59) | KRASTNFRSF1AF3CXCL12MCL1 | |
| SCHEMBL9112030 | 0.87 | MAOB (0.59) | KRASTNFRSF1AF3CXCL12MCL1 | |
| SCHEMBL9114466 | 0.86 | KDM4E (0.58) | KRASTNFRSF1AF3CXCL12MCL1 | |
| SCHEMBL13018517 | 0.85 | KRAS (1.00) | KRASTNFRSF1AF3CXCL12MCL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1995006628-A1 | TREATMENT AND PROPHYLAXIS OF DISEASES CAUSED BY PARASITES OR BACTERIA | STATENS SERUMINSTITUT (DK) | 1995-03-09 | — | — | WO | claimed |