Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 2/20 | 0.49 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.49 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.49 |
| ▸ | HTR1B | P28222 | 9/20 | 0.43 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA3 | P07451 | 1/20 | 0.33 |
| ▸ | CA4 | P22748 | 1/20 | 0.33 |
| ▸ | CA5A | P35218 | 1/20 | 0.33 |
| ▸ | CA7 | P43166 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.33 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9113907 | 0.80 | CHRM2 (0.48) | CHRM2CHRM1CHRM3HTR1BCYP2A6 | |
| SCHEMBL25235422 | 0.79 | CHRM2 (0.60) | CHRM2CHRM1CHRM3HTR1BCYP2A6 | |
| SCHEMBL29957913 | 0.79 | CHRM2 (0.60) | CHRM2CHRM1CHRM3HTR1BCYP2A6 | |
| SCHEMBL9111859 | 0.78 | HTR1B (0.43) | CHRM2CHRM1CHRM3HTR1BCYP2A6 | |
| SCHEMBL9113881 | 0.77 | CHRM2 (0.52) | CHRM2CHRM1CHRM3HTR1BCYP2A6 | |
| SCHEMBL2090147 | 0.77 | CHRM2 (0.55) | CHRM2CHRM1CHRM3HTR1BCYP2A6 | |
| SCHEMBL8040625 | 0.76 | HTR1B (0.53) | CHRM2CHRM1CHRM3HTR1BCYP2A6 | |
| SCHEMBL9111285 | 0.73 | HTR1B (0.44) | CHRM2CHRM1CHRM3HTR1BCYP2A6 | |
| SCHEMBL25240905 | 0.73 | CHRM2 (0.62) | CHRM2CHRM1CHRM3HTR1BCYP2A6 | |
| SCHEMBL14756115 | 0.73 | CHRM2 (0.53) | CHRM2CHRM1CHRM3HTR1BCYP2A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0670831-A1 | QUINOXALINE DERIVATIVE AS ANTIDIABETIC AGENT | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1995-09-13 | — | — | EP | disclosed |
| WO-1995009159-A1 | QUINOXALINE DERIVATIVE AS ANTIDIABETIC AGENT | OTSUKA PHARMACEUTICAL COMPANY, LIMITED (JP) | 1995-04-06 | — | — | WO | disclosed |