Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A1 | P04798 | 5/20 | 0.61 |
| ▸ | CYP1B1 | Q16678 | 5/20 | 0.61 |
| ▸ | DPP4 | P27487 | 5/20 | 0.56 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.55 |
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.52 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | BCHE | P06276 | 1/20 | 0.45 |
| ▸ | ACHE | P22303 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9111061 | 1.00 | CYP1A1 (0.61) | CYP1A1CYP1B1DPP4ABCG2TNFRSF1A | |
| SCHEMBL9113886 | 0.91 | CYP1A1 (0.59) | CYP1A1CYP1B1DPP4ABCG2TNFRSF1A | |
| SCHEMBL9113888 | 0.91 | CYP1A1 (0.59) | CYP1A1CYP1B1DPP4ABCG2TNFRSF1A | |
| SCHEMBL9115649 | 0.90 | DPP4 (0.56) | CYP1A1CYP1B1DPP4ABCG2TNFRSF1A | |
| SCHEMBL9113953 | 0.88 | DPP4 (0.56) | CYP1A1CYP1B1DPP4ABCG2PTPN1 | |
| SCHEMBL9115655 | 0.88 | DPP4 (0.56) | CYP1A1CYP1B1DPP4ABCG2PTPN1 | |
| SCHEMBL9113779 | 0.87 | CYP1A1 (0.70) | CYP1A1CYP1B1DPP4ABCG2TNFRSF1A | |
| SCHEMBL9112511 | 0.86 | CYP1A1 (0.52) | CYP1A1CYP1B1DPP4ABCG2PTPN1 | |
| SCHEMBL7185741 | 0.85 | PTPN1 (0.56) | CYP1A1CYP1B1TNFRSF1APTPN1MAPT | |
| SCHEMBL7796233 | 0.85 | PTPN1 (0.56) | CYP1A1CYP1B1TNFRSF1APTPN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1995006628-A1 | TREATMENT AND PROPHYLAXIS OF DISEASES CAUSED BY PARASITES OR BACTERIA | STATENS SERUMINSTITUT (DK) | 1995-03-09 | — | — | WO | claimed |
| WO-1995006628-A1 | TREATMENT AND PROPHYLAXIS OF DISEASES CAUSED BY PARASITES OR BACTERIA | STATENS SERUMINSTITUT (DK) | 1995-03-09 | — | — | WO | disclosed |