Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | HTR1A | P08908 | 2/20 | 0.41 |
| ▸ | HTR2A | P28223 | 2/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MLNR | O43193 | 1/20 | 0.41 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.41 |
| ▸ | EGFR | P00533 | 1/20 | 0.41 |
| ▸ | FYN | P06241 | 1/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.41 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9109449 | 0.76 | CYP2D6 (0.42) | CYP2D6KMT2AMEN1LMNATP53 | |
| SCHEMBL9114620 | 0.76 | CYP2D6 (0.32) | CYP2D6KMT2AMEN1LMNATP53 | |
| SCHEMBL7349463 | 0.73 | KMT2A (0.46) | CYP2D6KMT2AMEN1LMNATP53 | |
| SCHEMBL21556543 | 0.73 | CYP2D6 (0.46) | CYP2D6KMT2AMEN1LMNATP53 | |
| SCHEMBL9111943 | 0.72 | KMT2A (0.36) | CYP2D6KMT2AMEN1LMNATP53 | |
| SCHEMBL5062322 | 0.72 | CYP2D6 (0.44) | CYP2D6KMT2AMEN1LMNATP53 | |
| SCHEMBL6413011 | 0.70 | KMT2A (0.41) | CYP2D6KMT2AMEN1LMNATP53 | |
| SCHEMBL5932936 | 0.69 | CYP2D6 (0.44) | CYP2D6KMT2AMEN1LMNATP53 | |
| Hydrochloric Acid SCHEMBL29753604 | 0.68 | KMT2A (0.41) | CYP2D6KMT2AMEN1LMNATP53 | |
| SCHEMBL7122129 | 0.68 | CYP2D6 (0.41) | CYP2D6KMT2AMEN1LMNATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0670831-A1 | QUINOXALINE DERIVATIVE AS ANTIDIABETIC AGENT | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1995-09-13 | — | — | EP | disclosed |
| WO-1995009159-A1 | QUINOXALINE DERIVATIVE AS ANTIDIABETIC AGENT | OTSUKA PHARMACEUTICAL COMPANY, LIMITED (JP) | 1995-04-06 | — | — | WO | disclosed |