Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 8/20 | 0.78 |
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.67 |
| ▸ | ABCG2 | Q9UNQ0 | 3/20 | 0.66 |
| ▸ | DPP4 | P27487 | 3/20 | 0.62 |
| ▸ | MAOB | P27338 | 1/20 | 0.60 |
| ▸ | MAPT | P10636 | 3/20 | 0.58 |
| ▸ | LMNA | P02545 | 2/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.58 |
| ▸ | HPGD | P15428 | 1/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
| ▸ | ATM | Q13315 | 1/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.58 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.58 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.58 |
| ▸ | NPC1 | O15118 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
| ▸ | RAB9A | P51151 | 1/20 | 0.57 |
| ▸ | IDH1 | O75874 | 1/20 | 0.57 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.57 |
| ▸ | UGT1A1 | P22309 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7184962 | 0.90 | PTPN1 (0.67) | PTPN1TNFRSF1AABCG2DPP4IDH1 | |
| SCHEMBL7184954 | 0.90 | PTPN1 (0.67) | PTPN1TNFRSF1AABCG2DPP4IDH1 | |
| SCHEMBL7184285 | 0.90 | PTPN1 (0.78) | PTPN1ABCG2DPP4MAOBCYP1A1 | |
| SCHEMBL7184292 | 0.90 | PTPN1 (0.78) | PTPN1ABCG2DPP4MAOBCYP1A1 | |
| SCHEMBL9114676 | 0.89 | DPP4 (0.66) | PTPN1ABCG2DPP4MAOBMAPT | |
| SCHEMBL9113945 | 0.89 | PTPN1 (0.64) | PTPN1TNFRSF1AABCG2DPP4MAOB | |
| SCHEMBL7185085 | 0.89 | ABCG2 (0.64) | PTPN1TNFRSF1AABCG2DPP4CYP1A1 | |
| SCHEMBL7185074 | 0.89 | ABCG2 (0.64) | PTPN1TNFRSF1AABCG2DPP4CYP1A1 | |
| SCHEMBL7177707 | 0.88 | PTPN1 (0.70) | PTPN1TNFRSF1AABCG2DPP4CYP1A1 | |
| SCHEMBL7177703 | 0.88 | PTPN1 (0.70) | PTPN1TNFRSF1AABCG2DPP4CYP1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1995006628-A1 | TREATMENT AND PROPHYLAXIS OF DISEASES CAUSED BY PARASITES OR BACTERIA | STATENS SERUMINSTITUT (DK) | 1995-03-09 | — | — | WO | claimed |
| WO-1995006628-A1 | TREATMENT AND PROPHYLAXIS OF DISEASES CAUSED BY PARASITES OR BACTERIA | STATENS SERUMINSTITUT (DK) | 1995-03-09 | — | — | WO | disclosed |