Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.59 |
| ▸ | LMNA | P02545 | 2/20 | 0.59 |
| ▸ | MAPT | P10636 | 2/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.59 |
| ▸ | CYP1A1 | P04798 | 7/20 | 0.57 |
| ▸ | CYP1B1 | Q16678 | 7/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.57 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.57 |
| ▸ | ABCG2 | Q9UNQ0 | 3/20 | 0.57 |
| ▸ | MAOB | P27338 | 8/20 | 0.51 |
| ▸ | MAOA | P21397 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9112046 | 1.00 | KDM4E (0.59) | KDM4ELMNAMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL9112805 | 0.94 | ABCG2 (0.59) | KDM4ELMNAMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL9112419 | 0.92 | ABCG2 (0.57) | KDM4ELMNAMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL9114342 | 0.90 | KDM4E (0.57) | KDM4ELMNAMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL9114344 | 0.90 | KDM4E (0.57) | KDM4ELMNAMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL9114565 | 0.89 | MAPT (0.56) | KDM4ELMNAMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL9114573 | 0.89 | MAPT (0.56) | KDM4ELMNAMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL9111831 | 0.87 | KDM4E (0.69) | KDM4ELMNAMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL9111826 | 0.87 | KDM4E (0.69) | KDM4ELMNAMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL9113320 | 0.87 | ABCG2 (0.61) | KDM4ELMNAMAPTALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1995006628-A1 | TREATMENT AND PROPHYLAXIS OF DISEASES CAUSED BY PARASITES OR BACTERIA | STATENS SERUMINSTITUT (DK) | 1995-03-09 | — | — | WO | disclosed |