SCHEMBL9112573

SCHEMBL9112573

CCCCOc1cc(OCCCC)c(C=CC(=O)c2ccc(OCCC)cc2)cc1C

nearest known ligand 0.59

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
DPP4 P27487 5/20 0.59
PTPN1 P18031 5/20 0.59
ABCG2 Q9UNQ0 2/20 0.55
CYP1A1 P04798 2/20 0.53
CYP1B1 Q16678 2/20 0.53
BCHE P06276 4/20 0.49
ACHE P22303 2/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9111754 0.98 DPP4 (0.61) DPP4PTPN1ABCG2CYP1A1CYP1B1
SCHEMBL9113737 0.93 DPP4 (0.59) DPP4PTPN1ABCG2CYP1A1CYP1B1
SCHEMBL9112659 0.93 DPP4 (0.56) DPP4PTPN1ABCG2CYP1A1CYP1B1
SCHEMBL9113077 0.93 DPP4 (0.56) DPP4PTPN1ABCG2
SCHEMBL9113746 0.93 DPP4 (0.59) DPP4PTPN1ABCG2CYP1A1CYP1B1
SCHEMBL9113194 0.91 DPP4 (0.59) DPP4PTPN1ABCG2CYP1A1CYP1B1
SCHEMBL9114453 0.91 DPP4 (0.59) DPP4PTPN1ABCG2CYP1A1CYP1B1
SCHEMBL7180067 0.89 ABCG2 (0.59) DPP4PTPN1ABCG2
SCHEMBL7185133 0.89 PTPN1 (0.56) DPP4PTPN1ABCG2CYP1A1CYP1B1
SCHEMBL7183883 0.89 PTPN1 (0.56) DPP4PTPN1ABCG2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1995006628-A1 TREATMENT AND PROPHYLAXIS OF DISEASES CAUSED BY PARASITES OR BACTERIA STATENS SERUMINSTITUT (DK) 1995-03-09 WO claimed
WO-1995006628-A1 TREATMENT AND PROPHYLAXIS OF DISEASES CAUSED BY PARASITES OR BACTERIA STATENS SERUMINSTITUT (DK) 1995-03-09 WO disclosed