Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | GGPS1 | O95749 | 7/20 | 0.38 |
| ▸ | FDPS | P14324 | 10/20 | 0.36 |
| ▸ | SMPD1 | P17405 | 4/20 | 0.35 |
| ▸ | CES2 | O00748 | 1/20 | 0.35 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.35 |
| ▸ | LPAR3 | Q9UBY5 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8008433 | 1.00 | TSHR (0.39) | TSHRGGPS1FDPSSMPD1CES2 | |
| SCHEMBL9004671 | 1.00 | TSHR (0.39) | TSHRGGPS1FDPSSMPD1CES2 | |
| SCHEMBL18699075 | 0.89 | — | — | |
| SCHEMBL14046812 | 0.81 | — | — | |
| SCHEMBL2109068 | 0.78 | GGPS1 (0.42) | TSHRGGPS1FDPSSMPD1LPAR1 | |
| SCHEMBL2110488 | 0.78 | GGPS1 (0.42) | TSHRGGPS1FDPSSMPD1LPAR1 | |
| SCHEMBL93146 | 0.78 | GGPS1 (0.42) | TSHRGGPS1FDPSSMPD1LPAR1 | |
| SCHEMBL93198 | 0.78 | GGPS1 (0.42) | TSHRGGPS1FDPSSMPD1LPAR1 | |
| SCHEMBL2107760 | 0.78 | GGPS1 (0.42) | TSHRGGPS1FDPSSMPD1LPAR1 | |
| SCHEMBL2110793 | 0.78 | GGPS1 (0.42) | TSHRGGPS1FDPSSMPD1LPAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0637990-A1 | DIAPHRAGM BASED ON GRAFT COPOLYMERS. | GEESTHACHT GKSS FORSCHUNG (DE) | 1995-02-15 | — | — | EP | disclosed |