Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.73 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.73 |
| ▸ | LMNA | P02545 | 2/20 | 0.73 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.73 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.73 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.64 |
| ▸ | MAOB | P27338 | 8/20 | 0.62 |
| ▸ | MAOA | P21397 | 1/20 | 0.57 |
| ▸ | KRAS | P01116 | 1/20 | 0.56 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.56 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.56 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.56 |
| ▸ | DPP4 | P27487 | 2/20 | 0.54 |
| ▸ | NPC1 | O15118 | 2/20 | 0.54 |
| ▸ | RAB9A | P51151 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9112680 | 1.00 | MAPT (0.73) | MAPTKDM4ELMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL9114996 | 0.93 | MAPT (0.65) | MAPTKDM4ELMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL9115002 | 0.93 | MAPT (0.65) | MAPTKDM4ELMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL9114410 | 0.91 | KDM4E (0.60) | MAPTKDM4ELMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL9113968 | 0.91 | PTPN1 (0.64) | MAPTKDM4ELMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL9114745 | 0.91 | MAPT (0.63) | MAPTKDM4ELMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL9113961 | 0.91 | PTPN1 (0.64) | MAPTKDM4ELMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL9114998 | 0.91 | KRAS (0.68) | MAPTKDM4ELMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL9114991 | 0.91 | KRAS (0.68) | MAPTKDM4ELMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL9115765 | 0.89 | MAPT (0.60) | MAPTKDM4ELMNAALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1995006628-A1 | TREATMENT AND PROPHYLAXIS OF DISEASES CAUSED BY PARASITES OR BACTERIA | STATENS SERUMINSTITUT (DK) | 1995-03-09 | — | — | WO | claimed |