Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KRAS | P01116 | 1/20 | 0.66 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.62 |
| ▸ | TNFRSF1A | P19438 | 3/20 | 0.62 |
| ▸ | F3 | P13726 | 2/20 | 0.61 |
| ▸ | CXCL12 | P48061 | 1/20 | 0.60 |
| ▸ | MAOB | P27338 | 5/20 | 0.59 |
| ▸ | MAOA | P21397 | 2/20 | 0.59 |
| ▸ | MAPT | P10636 | 3/20 | 0.57 |
| ▸ | MEN1 | O00255 | 3/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.57 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.57 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.57 |
| ▸ | XDH | P47989 | 2/20 | 0.56 |
| ▸ | P4HB | P07237 | 1/20 | 0.56 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 1/20 | 0.56 |
| ▸ | CA1 | P00915 | 1/20 | 0.55 |
| ▸ | CA2 | P00918 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9113160 | 1.00 | KRAS (0.66) | KRASMCL1TNFRSF1AF3CXCL12 | |
| SCHEMBL9112454 | 0.89 | KRAS (0.64) | KRASMCL1TNFRSF1AF3CXCL12 | |
| SCHEMBL9110762 | 0.87 | MAPT (0.55) | MCL1F3CXCL12MAOBMAOA | |
| SCHEMBL9110769 | 0.87 | MAPT (0.55) | MCL1F3CXCL12MAOBMAOA | |
| SCHEMBL9113477 | 0.86 | MAPT (0.65) | MAOBMAOAMAPTKMT2AALDH1A1 | |
| SCHEMBL9113482 | 0.86 | MAPT (0.65) | MAOBMAOAMAPTKMT2AALDH1A1 | |
| SCHEMBL9113865 | 0.85 | TNFRSF1A (0.61) | TNFRSF1AF3MAOBMAPTALDH1A1 | |
| SCHEMBL9113870 | 0.85 | TNFRSF1A (0.61) | TNFRSF1AF3MAOBMAPTALDH1A1 | |
| SCHEMBL9115310 | 0.84 | KRAS (0.59) | KRASMCL1TNFRSF1AF3CXCL12 | |
| SCHEMBL9113683 | 0.84 | ABCG2 (0.60) | MAOBMAOAMAPTALDH1A1CYP1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1995006628-A1 | TREATMENT AND PROPHYLAXIS OF DISEASES CAUSED BY PARASITES OR BACTERIA | STATENS SERUMINSTITUT (DK) | 1995-03-09 | — | — | WO | claimed |