Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNFRSF1A | P19438 | 2/20 | 0.58 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.56 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.55 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.55 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 3/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | ATM | Q13315 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | F3 | P13726 | 1/20 | 0.52 |
| ▸ | MAOB | P27338 | 4/20 | 0.52 |
| ▸ | DPP4 | P27487 | 2/20 | 0.52 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.51 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.51 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.51 |
| ▸ | MAOA | P21397 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9115677 | 0.89 | CAPN1 (0.50) | TNFRSF1AABCG2GABRA3GABRA2GABRB2 | |
| SCHEMBL9113870 | 0.88 | TNFRSF1A (0.61) | TNFRSF1AABCG2GABRA3GABRA2GABRB2 | |
| SCHEMBL9113865 | 0.88 | TNFRSF1A (0.61) | TNFRSF1AABCG2GABRA3GABRA2GABRB2 | |
| SCHEMBL9112516 | 0.88 | TNFRSF1A (0.67) | TNFRSF1AABCG2GABRA3GABRA2GABRB2 | |
| SCHEMBL9113296 | 0.88 | MAOB (0.53) | ABCG2MAPTLMNASMN1; SMN2KDM4E | |
| SCHEMBL9111792 | 0.86 | DPP4 (0.54) | ABCG2MAOBDPP4PTPN1CYP1A1 | |
| SCHEMBL7179843 | 0.85 | TNFRSF1A (0.71) | TNFRSF1AABCG2GABRA3GABRA2GABRB2 | |
| SCHEMBL7179848 | 0.85 | TNFRSF1A (0.71) | TNFRSF1AABCG2GABRA3GABRA2GABRB2 | |
| SCHEMBL7802397 | 0.85 | ABCG2 (0.69) | TNFRSF1AABCG2GABRA3GABRA2GABRB2 | |
| SCHEMBL7802395 | 0.85 | ABCG2 (0.69) | TNFRSF1AABCG2GABRA3GABRA2GABRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1995006628-A1 | TREATMENT AND PROPHYLAXIS OF DISEASES CAUSED BY PARASITES OR BACTERIA | STATENS SERUMINSTITUT (DK) | 1995-03-09 | — | — | WO | claimed |