SCHEMBL9113602

SCHEMBL9113602

CCN1C(=O)CC[C@@]2(C)C1CC[C@@H]1[C@H]2CC[C@]2(C)C(COC(=O)NC)CC[C@@H]12

nearest known ligand 0.58

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
SRD5A1 P18405 1/20 0.46
SRD5A2 P31213 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9113599 1.00 SRD5A1 (0.46) SRD5A1SRD5A2
SCHEMBL8722259 0.89 SRD5A1 (0.56) SRD5A1SRD5A2
SCHEMBL8722257 0.89 SRD5A1 (0.56) SRD5A1SRD5A2
SCHEMBL7745372 0.79 SRD5A2 (0.60) SRD5A1SRD5A2
SCHEMBL7745374 0.79 SRD5A2 (0.60) SRD5A1SRD5A2
SCHEMBL7749990 0.78 SRD5A1 (0.59) SRD5A1SRD5A2
SCHEMBL7749994 0.78 SRD5A1 (0.59) SRD5A1SRD5A2
SCHEMBL7750310 0.75 SRD5A1 (0.51) SRD5A1SRD5A2
SCHEMBL7745356 0.75 SRD5A1 (0.51) SRD5A1SRD5A2
SCHEMBL7750334 0.75 SRD5A1 (0.56) SRD5A1SRD5A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0649306-A4 ESTER DERIVATIVES OF 4-AZA-STEROIDS. MERCK & CO INC (US) 1995-08-23 EP disclosed
EP-0649306-A1 ESTER DERIVATIVES OF 4-AZA-STEROIDS MERCK & CO. INC. (US) 1995-04-26 EP disclosed