Tetrachloroethylene

Tetrachloroethylene

SCHEMBL9113692

CCCC#N.ClC(Cl)=C(Cl)Cl

nearest known ligand 0.48

Full drug profile on Sugi Atlas →

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.48
ALDH1A1 P00352 2/20 0.39
TDP1 Q9NUW8 1/20 0.39
CYP3A4 P08684 1/20 0.38
LOX P28300 1/20 0.32
LOXL3 P58215 1/20 0.32
LOXL2 Q9Y4K0 1/20 0.32
MEN1 O00255 1/20 0.31
KMT2A Q03164 1/20 0.31
NLRP3 Q96P20 1/20 0.31
MCL1 Q07820 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Water SCHEMBL11344535 0.84
Water SCHEMBL28254801 0.84 TSHR (0.62) TSHRALDH1A1TDP1CYP3A4LOX
SCHEMBL28208107 0.84 TSHR (0.62) TSHRALDH1A1TDP1CYP3A4LOX
SCHEMBL22628 0.84
Alcohol SCHEMBL28073222 0.81
Charcoal, Activated SCHEMBL31050920 0.81
SCHEMBL32674549 0.81
SCHEMBL4161702 0.81 TSHR (0.59) TSHRALDH1A1TDP1CYP3A4LOX
Hydrochloric Acid SCHEMBL7224294 0.81
Propane SCHEMBL8012439 0.81

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1995016740-A1 HYDROGEN FLUORIDE COMPOSITION MOBIL OIL CORPORATION (US) 1995-06-22 WO disclosed