Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 1/20 | 0.39 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.38 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.38 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.38 |
| ▸ | EGFR | P00533 | 1/20 | 0.37 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | MMP12 | P39900 | 1/20 | 0.36 |
| ▸ | MMP13 | P45452 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | ELANE | P08246 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27678012 | 0.87 | CYP19A1 (0.42) | CYP19A1PRSS1PRSS2PRSS3EGFR | |
| SCHEMBL1582633 | 0.76 | CYP3A4 (0.41) | ALDH1A1KMT2ACASP1SMN1; SMN2HTT | |
| SCHEMBL27897138 | 0.76 | ELANE (0.47) | CYP19A1ALDH1A1MAPTMMP12MMP13 | |
| SCHEMBL27697637 | 0.76 | ELANE (0.47) | CYP19A1ALDH1A1MAPTMMP12MMP13 | |
| SCHEMBL27955868 | 0.76 | CYP19A1 (0.44) | CYP19A1PRSS1PRSS2PRSS3ALDH1A1 | |
| SCHEMBL27628863 | 0.76 | ELANE (0.47) | CYP19A1ALDH1A1MAPTMMP12MMP13 | |
| SCHEMBL4654692 | 0.76 | GABRR1 (0.50) | CYP19A1PRSS1PRSS2PRSS3ALDH1A1 | |
| SCHEMBL628767 | 0.75 | PDGFRB (0.36) | ALDH1A1MAPTSMN1; SMN2LMNAHSD17B10 | |
| SCHEMBL27833901 | 0.75 | CYP19A1 (0.49) | CYP19A1PRSS1PRSS2PRSS3EGFR | |
| SCHEMBL31517798 | 0.74 | PDGFRB (0.35) | ALDH1A1MAPTSMN1; SMN2LMNAHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1995011898-A1 | CONDENSED PYRIDINE TYPE MEVALONOLACTONE INTERMEDIATE AND PROCESS FOR ITS PRODUCTION | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1995-05-04 | — | — | WO | disclosed |