Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 2/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.39 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.39 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | IL4I1 | Q96RQ9 | 1/20 | 0.38 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.38 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13134181 | 0.81 | MAOB (0.49) | MAOBCA2CYP1A2CYP3A4CYP2C8 | |
| SCHEMBL30633849 | 0.78 | MAOB (0.53) | MAOBCA2CYP17A1CYP19A1CYP11B1 | |
| SCHEMBL1299218 | 0.78 | MAOB (0.53) | MAOBCA2CYP17A1CYP19A1CYP11B1 | |
| SCHEMBL2092249 | 0.75 | MAOB (0.53) | MAOBCA2CYP17A1CYP19A1CYP11B1 | |
| SCHEMBL6511946 | 0.72 | MAOB (0.71) | MAOBCA2CYP17A1CYP19A1CYP11B1 | |
| SCHEMBL30396397 | 0.72 | HTR1D (0.53) | MAOBCA2CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL7360353 | 0.72 | MAOB (0.50) | MAOBCA2CYP17A1CYP19A1CYP11B1 | |
| SCHEMBL140189 | 0.72 | HTR1D (0.53) | MAOBCA2CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL19110102 | 0.71 | MAOB (0.46) | MAOBCA2CYP1A2CYP3A4CYP2C8 | |
| SCHEMBL15075824 | 0.71 | MAOB (0.53) | MAOBCA2CYP17A1CYP19A1CYP11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0670831-A1 | QUINOXALINE DERIVATIVE AS ANTIDIABETIC AGENT | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1995-09-13 | — | — | EP | disclosed |
| WO-1995009159-A1 | QUINOXALINE DERIVATIVE AS ANTIDIABETIC AGENT | OTSUKA PHARMACEUTICAL COMPANY, LIMITED (JP) | 1995-04-06 | — | — | WO | disclosed |