Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 3/20 | 0.51 |
| ▸ | CA1 | P00915 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 1/20 | 0.49 |
| ▸ | F3 | P13726 | 3/20 | 0.47 |
| ▸ | CTSL | P07711 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 4/20 | 0.45 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 5/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | P4HB | P07237 | 1/20 | 0.45 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.45 |
| ▸ | XDH | P47989 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | IDH1 | O75874 | 1/20 | 0.45 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.45 |
| ▸ | UGT1A1 | P22309 | 1/20 | 0.45 |
| ▸ | DPP4 | P27487 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9114475 | 1.00 | PTPN1 (0.51) | PTPN1CA1CA2F3CTSL | |
| SCHEMBL9114106 | 0.89 | KRAS (0.58) | PTPN1F3MAOBABCG2MAPT | |
| SCHEMBL9114101 | 0.89 | KRAS (0.58) | PTPN1F3MAOBABCG2MAPT | |
| SCHEMBL9113603 | 0.87 | PTPN1 (0.63) | PTPN1CA1CA2F3CTSL | |
| SCHEMBL9113607 | 0.87 | PTPN1 (0.63) | PTPN1CA1CA2F3CTSL | |
| SCHEMBL9113656 | 0.87 | PTPN1 (0.53) | PTPN1MAOBABCG2MAPTALDH1A1 | |
| SCHEMBL9113665 | 0.87 | PTPN1 (0.53) | PTPN1MAOBABCG2MAPTALDH1A1 | |
| SCHEMBL9113411 | 0.87 | MAPT (0.59) | PTPN1MAOBABCG2MAPTKMT2A | |
| SCHEMBL9115271 | 0.85 | ABCG2 (0.55) | PTPN1MAOBABCG2MAPTALDH1A1 | |
| SCHEMBL9114787 | 0.85 | ABCG2 (0.50) | CA1CA2F3CTSLMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1995006628-A1 | TREATMENT AND PROPHYLAXIS OF DISEASES CAUSED BY PARASITES OR BACTERIA | STATENS SERUMINSTITUT (DK) | 1995-03-09 | — | — | WO | claimed |
| WO-1995006628-A1 | TREATMENT AND PROPHYLAXIS OF DISEASES CAUSED BY PARASITES OR BACTERIA | STATENS SERUMINSTITUT (DK) | 1995-03-09 | — | — | WO | disclosed |