Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAGI3 | Q5TCQ9 | 1/20 | 0.69 |
| ▸ | EDNRA | P25101 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | ACE | P12821 | 2/20 | 0.51 |
| ▸ | ECE1 | P42892 | 5/20 | 0.50 |
| ▸ | GHSR | Q92847 | 1/20 | 0.48 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.47 |
| ▸ | MMP1 | P03956 | 1/20 | 0.47 |
| ▸ | MMP3 | P08254 | 1/20 | 0.47 |
| ▸ | MMP9 | P14780 | 1/20 | 0.47 |
| ▸ | MMP8 | P22894 | 1/20 | 0.47 |
| ▸ | CASP1 | P29466 | 1/20 | 0.47 |
| ▸ | CASP3 | P42574 | 1/20 | 0.47 |
| ▸ | CASP4 | P49662 | 1/20 | 0.47 |
| ▸ | CASP5 | P51878 | 1/20 | 0.47 |
| ▸ | CASP7 | P55210 | 1/20 | 0.47 |
| ▸ | CASP9 | P55211 | 1/20 | 0.47 |
| ▸ | CASP6 | P55212 | 1/20 | 0.47 |
| ▸ | CASP8 | Q14790 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9141715 | 1.00 | MAGI3 (0.69) | MAGI3EDNRAKMT2AL3MBTL1ACE | |
| SCHEMBL9114908 | 1.00 | MAGI3 (0.69) | MAGI3EDNRAKMT2AL3MBTL1ACE | |
| SCHEMBL9141706 | 1.00 | MAGI3 (0.69) | MAGI3EDNRAKMT2AL3MBTL1ACE | |
| SCHEMBL9110690 | 0.94 | MAGI3 (0.65) | MAGI3EDNRAKMT2AL3MBTL1ACE | |
| SCHEMBL9143425 | 0.94 | MAGI3 (0.65) | MAGI3EDNRAKMT2AL3MBTL1ACE | |
| SCHEMBL9143412 | 0.94 | MAGI3 (0.65) | MAGI3EDNRAKMT2AL3MBTL1ACE | |
| SCHEMBL9110705 | 0.94 | MAGI3 (0.65) | MAGI3EDNRAKMT2AL3MBTL1ACE | |
| SCHEMBL30051105 | 0.89 | ACE (0.56) | MAGI3EDNRAKMT2AL3MBTL1ACE | |
| SCHEMBL30051825 | 0.89 | ACE (0.64) | EDNRAKMT2AL3MBTL1ACEECE1 | |
| SCHEMBL38664666 | 0.88 | MAGI3 (0.57) | MAGI3EDNRAKMT2AL3MBTL1ACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5464935-A | Peptide inhibitors of selectin binding | CENTOCOR, INC. (US) | 1995-11-07 | — | — | US | disclosed |
| EP-0652897-A4 | PEPTIDE INHIBITORS OF SELECTIN BINDING. | CENTOCOR INC (US) | 1995-09-20 | — | — | EP | disclosed |
| EP-0652897-A1 | PEPTIDE INHIBITORS OF SELECTIN BINDING | CENTOCOR INC. (US) | 1995-05-17 | — | — | EP | disclosed |
| WO-1993024527-A1 | PEPTIDE INHIBITORS OF SELECTIN BINDING | CENTOCOR, INC. (US) | 1993-12-09 | — | — | WO | disclosed |