Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCG2 | Q9UNQ0 | 3/20 | 0.50 |
| ▸ | PDE4A | P27815 | 1/20 | 0.50 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.50 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.50 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.50 |
| ▸ | MAOB | P27338 | 3/20 | 0.49 |
| ▸ | F3 | P13726 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | CTSL | P07711 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 6/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | P4HB | P07237 | 1/20 | 0.46 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.46 |
| ▸ | XDH | P47989 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9115163 | 1.00 | ABCG2 (0.50) | ABCG2PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL9112916 | 0.88 | KRAS (0.59) | ABCG2PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL9112912 | 0.88 | KRAS (0.59) | ABCG2PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL9112383 | 0.87 | MAPT (0.61) | ABCG2MAOBLMNAPOLBMAPT | |
| SCHEMBL9112385 | 0.87 | MAPT (0.61) | ABCG2MAOBLMNAPOLBMAPT | |
| SCHEMBL9113950 | 0.86 | CA1 (0.59) | ABCG2MAOBF3LMNACA1 | |
| SCHEMBL9113951 | 0.86 | CA1 (0.59) | ABCG2MAOBF3LMNACA1 | |
| SCHEMBL9115375 | 0.86 | ABCG2 (0.58) | ABCG2MAOBLMNAMAPTALDH1A1 | |
| SCHEMBL9115380 | 0.86 | ABCG2 (0.58) | ABCG2MAOBLMNAMAPTALDH1A1 | |
| SCHEMBL9111984 | 0.85 | ABCG2 (0.61) | ABCG2PDE4APDE4BPDE4CPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1995006628-A1 | TREATMENT AND PROPHYLAXIS OF DISEASES CAUSED BY PARASITES OR BACTERIA | STATENS SERUMINSTITUT (DK) | 1995-03-09 | — | — | WO | claimed |
| WO-1995006628-A1 | TREATMENT AND PROPHYLAXIS OF DISEASES CAUSED BY PARASITES OR BACTERIA | STATENS SERUMINSTITUT (DK) | 1995-03-09 | — | — | WO | disclosed |