Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 9/20 | 0.56 |
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.53 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.51 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.50 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.50 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.50 |
| ▸ | MAOB | P27338 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | DPP4 | P27487 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9115678 | 1.00 | PTPN1 (0.56) | PTPN1TNFRSF1AABCG2GABRA3GABRA2 | |
| SCHEMBL9113069 | 0.91 | PTPN1 (0.53) | PTPN1ABCG2MAOBDPP4 | |
| SCHEMBL9112411 | 0.91 | PTPN1 (0.53) | PTPN1ABCG2MAOBDPP4 | |
| SCHEMBL9114615 | 0.90 | PTPN1 (0.56) | PTPN1ABCG2MAOBMAPTLMNA | |
| SCHEMBL9111705 | 0.90 | PTPN1 (0.56) | PTPN1TNFRSF1AABCG2 | |
| SCHEMBL9111700 | 0.90 | PTPN1 (0.56) | PTPN1TNFRSF1AABCG2 | |
| SCHEMBL9114610 | 0.90 | PTPN1 (0.56) | PTPN1ABCG2MAOBMAPTLMNA | |
| SCHEMBL9113333 | 0.88 | DPP4 (0.48) | PTPN1ABCG2DPP4 | |
| SCHEMBL9113326 | 0.88 | DPP4 (0.48) | PTPN1ABCG2DPP4 | |
| SCHEMBL9112327 | 0.87 | PTPN1 (0.65) | PTPN1TNFRSF1AABCG2GABRA3GABRA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1995006628-A1 | TREATMENT AND PROPHYLAXIS OF DISEASES CAUSED BY PARASITES OR BACTERIA | STATENS SERUMINSTITUT (DK) | 1995-03-09 | — | — | WO | claimed |