Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | HPGD | P15428 | 4/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | HTT | P42858 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | CA12 | O43570 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6241330 | 0.94 | CYP19A1 (0.54) | CYP19A1MAPTHPGDNPC1HTT | |
| SCHEMBL8670350 | 0.88 | CYP19A1 (0.59) | CYP19A1MAPTHPGDNPC1HTT | |
| SCHEMBL8519711 | 0.88 | CYP19A1 (0.59) | CYP19A1MAPTHPGDNPC1HTT | |
| SCHEMBL8672674 | 0.88 | CYP19A1 (0.59) | CYP19A1MAPTHPGDNPC1HTT | |
| SCHEMBL16755709 | 0.86 | CYP19A1 (0.58) | CYP19A1MAPTHPGDNPC1HTT | |
| SCHEMBL9077857 | 0.83 | HDAC3 (0.58) | CYP19A1MAPTHPGDNPC1HTT | |
| SCHEMBL31211720 | 0.82 | CYP19A1 (0.66) | CYP19A1MAPTHPGDNPC1HTT | |
| Phenol SCHEMBL9396776 | 0.81 | CYP19A1 (0.62) | CYP19A1MAPTHPGDNPC1HTT | |
| SCHEMBL1114801 | 0.81 | HDAC3 (0.61) | CYP19A1MAPTHPGDHTTSMN1; SMN2 | |
| SCHEMBL1919197 | 0.81 | HTT (0.65) | CYP19A1MAPTHTTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1995025731-A1 | NOVEL 3-(φ-(4-BENZOYLPIPERIDINO)ALKYL)-4H-BENZOPYRAN-4-ONES, PREPARATION AND THERAPEUTICAL USE THEREOF | PIERRE FABRE MEDICAMENT (FR) | 1995-09-28 | — | — | WO | disclosed |