Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE2A | O00408 | 1/20 | 0.35 |
| ▸ | DHODH | Q02127 | 3/20 | 0.33 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.33 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.33 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | SMURF2 | Q9HAU4 | 1/20 | 0.32 |
| ▸ | SMURF1 | Q9HCE7 | 1/20 | 0.32 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | CRACR2A | Q9BSW2 | 2/20 | 0.31 |
| ▸ | MGLL | Q99685 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8492663 | 0.92 | PDE2A (0.38) | PDE2ADHODHTAS1R3TAS1R1TAS1R2 | |
| SCHEMBL27294090 | 0.88 | PDE2A (0.34) | PDE2ADHODHTAS1R3TAS1R1TAS1R2 | |
| SCHEMBL8492634 | 0.88 | DHODH (0.34) | PDE2ADHODHMEN1KMT2AEPHX2 | |
| SCHEMBL9115217 | 0.86 | DHODH (0.32) | PDE2ADHODHMEN1KMT2AEPHX2 | |
| SCHEMBL8752758 | 0.86 | DHODH (0.38) | PDE2ADHODHCRHR1MEN1KMT2A | |
| SCHEMBL8491585 | 0.86 | DHODH (0.35) | PDE2ADHODHTAS1R3TAS1R1TAS1R2 | |
| SCHEMBL9116693 | 0.86 | PDE2A (0.33) | PDE2ADHODHMEN1KMT2AEPHX2 | |
| SCHEMBL8388508 | 0.85 | PDE2A (0.34) | PDE2ADHODHTAS1R3TAS1R1TAS1R2 | |
| SCHEMBL8892581 | 0.85 | PTGDR2 (0.34) | PDE2ATAS1R3TAS1R1TAS1R2MAPT | |
| SCHEMBL9069516 | 0.84 | PDE2A (0.35) | PDE2ADHODHTAS1R3TAS1R1TAS1R2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1995022903-A1 | NEW PESTICIDAL METHOD | RHONE-POULENC AGROCHIMIE (FR) | 1995-08-31 | — | — | WO | disclosed |