Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.47 |
| ▸ | RAB9A | P51151 | 6/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | GFER | P55789 | 1/20 | 0.47 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.47 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 4/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | CCR1 | P32246 | 2/20 | 0.37 |
| ▸ | CCR5 | P51681 | 2/20 | 0.37 |
| ▸ | CCR8 | P51685 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2438256 | 0.78 | PDE10A (0.58) | PDE10AKDM4ERAB9AALDH1A1MAPT | |
| SCHEMBL6840490 | 0.73 | PDE10A (1.00) | PDE10AKDM4ERAB9AALDH1A1MAPT | |
| SCHEMBL30606303 | 0.73 | PDE10A (1.00) | PDE10AKDM4ERAB9AALDH1A1MAPT | |
| SCHEMBL1741719 | 0.72 | CYP19A1 (0.79) | PDE10AKDM4ERAB9AALDH1A1MAPT | |
| SCHEMBL16159960 | 0.70 | PDE10A (0.48) | PDE10AKDM4ERAB9AALDH1A1MAPT | |
| SCHEMBL13020808 | 0.69 | PDE10A (0.64) | PDE10AKDM4ERAB9AALDH1A1MAPT | |
| SCHEMBL15825002 | 0.69 | PDE10A (0.64) | PDE10AKDM4ERAB9AALDH1A1MAPT | |
| SCHEMBL252304 | 0.69 | PDE10A (0.64) | PDE10AKDM4ERAB9AALDH1A1MAPT | |
| SCHEMBL31341159 | 0.69 | PDE10A (0.64) | PDE10AKDM4ERAB9AALDH1A1MAPT | |
| SCHEMBL21366511 | 0.69 | PDE10A (0.63) | PDE10AKDM4ERAB9AALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1995029929-A1 | NOVEL ERYTHROMYCIN DERIVATIVES, METHOD FOR THEIR PREPARATION AND THEIR USE AS DRUGS | ROUSSEL UCLAF (FR) | 1995-11-09 | — | — | WO | disclosed |