Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6833353 | 0.98 | EGFR (0.71) | EGFRRXFP1 | |
| SCHEMBL6839396 | 0.87 | EGFR (1.00) | EGFR | |
| SCHEMBL6806034 | 0.87 | EGFR (0.70) | EGFR | |
| SCHEMBL6839154 | 0.78 | EGFR (1.00) | EGFR | |
| SCHEMBL6837209 | 0.78 | EGFR (1.00) | EGFR | |
| SCHEMBL4361560 | 0.78 | EGFR (1.00) | EGFR | |
| SCHEMBL6833177 | 0.78 | EGFR (1.00) | EGFR | |
| SCHEMBL30715571 | 0.76 | ABCG2 (0.78) | EGFRRXFP1 | |
| SCHEMBL5564516 | 0.76 | ABCG2 (0.78) | EGFRRXFP1 | |
| SCHEMBL13621682 | 0.75 | EGFR (0.76) | EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1995019774-A1 | BICYCLIC COMPOUNDS CAPABLE OF INHIBITING TYROSINE KINASES OF THE EPIDERMAL GROWTH FACTOR RECEPTOR FAMILY | WARNER-LAMBERT COMPANY (US) | 1995-07-27 | — | — | WO | disclosed |