Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.61 |
| ▸ | HTT | P42858 | 1/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.61 |
| ▸ | USP2 | O75604 | 1/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | ELANE | P08246 | 2/20 | 0.54 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | NQO1 | P15559 | 1/20 | 0.50 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | ACACB | O00763 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | F2 | P00734 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | PLK1 | P53350 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18417199 | 1.00 | KMT2A (0.61) | KMT2AHTTSMN1; SMN2TDP1USP2 | |
| SCHEMBL12444455 | 0.94 | KMT2A (0.54) | KMT2AHTTSMN1; SMN2TDP1USP2 | |
| SCHEMBL11642256 | 0.93 | KMT2A (0.68) | KMT2AHTTSMN1; SMN2TDP1USP2 | |
| SCHEMBL1895159 | 0.92 | KMT2A (0.53) | KMT2AHTTSMN1; SMN2TDP1USP2 | |
| SCHEMBL18551974 | 0.92 | KMT2A (0.66) | KMT2AHTTSMN1; SMN2TDP1USP2 | |
| SCHEMBL11404207 | 0.89 | KMT2A (0.50) | KMT2AHTTSMN1; SMN2TDP1USP2 | |
| SCHEMBL7763807 | 0.89 | KMT2A (0.50) | KMT2AHTTSMN1; SMN2TDP1USP2 | |
| SCHEMBL2213018 | 0.89 | KMT2A (0.50) | KMT2AHTTSMN1; SMN2TDP1USP2 | |
| SCHEMBL13271014 | 0.88 | KMT2A (0.49) | KMT2AHTTSMN1; SMN2TDP1USP2 | |
| SCHEMBL11412276 | 0.88 | KMT2A (0.49) | KMT2AHTTSMN1; SMN2TDP1USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1995028410-A1 | BIOLOGICALLY ACTIVE COMPOSITION | HENKEL CORPORATION (US) | 1995-10-26 | — | — | WO | disclosed |