Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.54 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9689041 | 0.87 | CYSLTR2 (0.53) | CYSLTR2CYSLTR1 | |
| SCHEMBL9117940 | 0.86 | — | — | |
| SCHEMBL9585999 | 0.84 | — | — | |
| SCHEMBL9121313 | 0.84 | — | — | |
| SCHEMBL9121234 | 0.84 | — | — | |
| SCHEMBL9119548 | 0.83 | MAPK1 (0.55) | CYSLTR2CYSLTR1 | |
| SCHEMBL9118802 | 0.83 | MAPK1 (0.55) | CYSLTR2CYSLTR1 | |
| SCHEMBL9120740 | 0.83 | — | — | |
| SCHEMBL9120799 | 0.83 | — | — | |
| SCHEMBL9120087 | 0.83 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0480708-B1 | Hydroxyalkylquinoline ether acids as leukotriene antagonists | MERCK FROSST CANADA INC (CA) | 1995-10-11 | — | — | EP | disclosed |
| US-5266568-A | Hydroxyalkylquinoline ether acids as leukotriene antagonists | MERCK FROSST CANADA, INC. (CA) | 1993-11-30 | — | — | US | disclosed |
| EP-0480708-A2 | Hydroxyalkylquinoline ether acids as leukotriene antagonists | MERCK FROSST CANADA INC. (CA) | 1992-04-15 | — | — | EP | disclosed |