Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.47 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.45 |
| ▸ | PYGM | P11217 | 3/20 | 0.44 |
| ▸ | ADORA2B | P29275 | 3/20 | 0.44 |
| ▸ | PYGL | P06737 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9122440 | 0.95 | TSHR (0.60) | TSHRHSD17B10NPSR1KDM4EHPGD | |
| SCHEMBL9119964 | 0.89 | HTT (0.48) | TSHRHSD17B10NPSR1KDM4EHPGD | |
| SCHEMBL16187000 | 0.87 | HSP90AA1 (0.43) | TSHRHSD17B10NPSR1KDM4EHPGD | |
| SCHEMBL9121117 | 0.87 | TSHR (0.56) | TSHRHSD17B10NPSR1KDM4EHPGD | |
| SCHEMBL7934386 | 0.86 | TSHR (0.69) | TSHRHSD17B10NPSR1KDM4EHPGD | |
| SCHEMBL9120147 | 0.84 | NPSR1 (0.69) | TSHRHSD17B10NPSR1KDM4EHPGD | |
| SCHEMBL9363806 | 0.82 | HSP90AA1 (0.39) | TSHRHSD17B10NPSR1KDM4EHPGD | |
| SCHEMBL14986934 | 0.82 | TSHR (0.63) | TSHRHSD17B10NPSR1KDM4EHPGD | |
| SCHEMBL9117834 | 0.81 | TSHR (0.47) | TSHRHSD17B10NPSR1KDM4EHPGD | |
| SCHEMBL21116053 | 0.80 | HTT (0.71) | TSHRHSD17B10NPSR1KDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0451654-B1 | Use of N-alkylated 1,4-dihydropyridine carboxylic acid esters as drugs, new compounds and process for their preparation | BAYER AG (DE) | 1994-09-07 | — | — | EP | claimed |
| US-5234935-A | Preventing myocardial infarct | BAYER AKTIENGESELLSCHAFT (DE) | 1993-08-10 | — | — | US | claimed |
| US-5432185-A | Treating patients exhibiting acute or chronic ischaemic disorders associated with disorders of microcirculation, without lowering or increasing blood pressure | BAYER AKTIENGESELLSCHAFT (DE) | 1995-07-11 | — | — | US | disclosed |
| US-5234935-A | Preventing myocardial infarct | BAYER AKTIENGESELLSCHAFT (DE) | 1993-08-10 | — | — | US | disclosed |