Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | GRIN2D | O15399 | 11/20 | 0.39 |
| ▸ | GRIN3B | O60391 | 11/20 | 0.39 |
| ▸ | GRIN1 | Q05586 | 11/20 | 0.39 |
| ▸ | GRIN2A | Q12879 | 11/20 | 0.39 |
| ▸ | GRIN2B | Q13224 | 11/20 | 0.39 |
| ▸ | GRIN2C | Q14957 | 11/20 | 0.39 |
| ▸ | GRIN3A | Q8TCU5 | 11/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8872383 | 0.76 | KDM4E (0.42) | TSHRKDM4EMAPTTDP1BLM | |
| SCHEMBL9015233 | 0.72 | TSHR (0.36) | TSHRKDM4EMAPTTDP1BLM | |
| SCHEMBL10710731 | 0.72 | TSHR (0.65) | TSHRMAPTTDP1ALDH1A1GRIN2D | |
| SCHEMBL3476651 | 0.72 | TSHR (0.65) | TSHRMAPTTDP1ALDH1A1GRIN2D | |
| SCHEMBL9337605 | 0.71 | MAPT (0.38) | TSHRKDM4EMAPTTDP1ALDH1A1 | |
| SCHEMBL9221192 | 0.71 | HCRTR1 (0.43) | TSHRKDM4EMAPTTDP1ALDH1A1 | |
| SCHEMBL14608804 | 0.70 | MEN1 (0.47) | MAPTALDH1A1GRIN2DGRIN3BGRIN1 | |
| SCHEMBL4706746 | 0.69 | TSHR (0.55) | TSHRMAPTTDP1ALDH1A1GRIN2D | |
| Pentachloronitrobenzene SCHEMBL69247 | 0.69 | TSHR (0.62) | TSHRMAPTTDP1ALDH1A1GRIN2D | |
| SCHEMBL9222727 | 0.68 | HCRTR1 (0.50) | TSHRKDM4EMAPTTDP1BLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0372263-B1 | Pyrrole carbonitrile and nitro-pyrrole insecticidal, acaricidal and molluscicidal agents and methods for the preparation thereof | AMERICAN CYANAMID CO (US) | 1995-02-15 | — | — | EP | claimed |
| US-5162308-A | Pyrrole carbonitrile and nitropyrrole insecticidal, acaricidal and molluscicidal agents and methods for the preparation thereof | AMERICAN CYANAMID COMPANY (US) | 1992-11-10 | — | — | US | claimed |
| EP-0372263-A2 | Pyrrole carbonitrile and nitro-pyrrole insecticidal, acaricidal and molluscicidal agents and methods for the preparation thereof | AMERICAN CYANAMID COMPANY (US) | 1990-06-13 | — | — | EP | claimed |
| EP-0372263-B1 | Pyrrole carbonitrile and nitro-pyrrole insecticidal, acaricidal and molluscicidal agents and methods for the preparation thereof | AMERICAN CYANAMID CO (US) | 1995-02-15 | — | — | EP | disclosed |
| US-5204332-A | PYRROLE CARBONITRILE AND NITROPYRROLE INSECTICIDAL AND ACARICIDAL AND MOLLUSCICIDAL AGENTS | AMERICAN CYANAMID COMPANY (US) | 1993-04-20 | — | — | US | disclosed |
| US-5162308-A | Pyrrole carbonitrile and nitropyrrole insecticidal, acaricidal and molluscicidal agents and methods for the preparation thereof | AMERICAN CYANAMID COMPANY (US) | 1992-11-10 | — | — | US | disclosed |
| EP-0372263-A2 | Pyrrole carbonitrile and nitro-pyrrole insecticidal, acaricidal and molluscicidal agents and methods for the preparation thereof | AMERICAN CYANAMID COMPANY (US) | 1990-06-13 | — | — | EP | disclosed |