Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN4A | P35499 | 9/20 | 0.49 |
| ▸ | SCN8A | Q9UQD0 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | SCN1A | P35498 | 2/20 | 0.49 |
| ▸ | SCN5A | Q14524 | 2/20 | 0.49 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.49 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.49 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.49 |
| ▸ | KCNK2 | O95069 | 1/20 | 0.49 |
| ▸ | GBA1 | P04062 | 1/20 | 0.49 |
| ▸ | MAOA | P21397 | 1/20 | 0.49 |
| ▸ | HTR2A | P28223 | 1/20 | 0.49 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.49 |
| ▸ | HTR2B | P41595 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9125923 | 0.83 | HTR1B (0.49) | LMNATSHRALDH1A1KDM4EL3MBTL1 | |
| SCHEMBL9125640 | 0.83 | TDP1 (0.51) | SCN4ALMNACYP1A2CYP2D6TSHR | |
| SCHEMBL9120582 | 0.77 | SMN1; SMN2 (0.52) | LMNACYP2C9ALDH1A1KDM4EL3MBTL1 | |
| SCHEMBL18997834 | 0.77 | SCN4A (0.55) | SCN4ASCN8ALMNASCN1ASCN5A | |
| SCHEMBL9121381 | 0.77 | TDP1 (0.46) | LMNAALDH1A1L3MBTL1 | |
| SCHEMBL3400079 | 0.75 | SCN4A (0.54) | SCN4ASCN8ALMNASCN1ASCN5A | |
| SCHEMBL3399258 | 0.75 | SCN4A (0.56) | SCN4ASCN8ALMNASCN1ASCN5A | |
| SCHEMBL9123362 | 0.75 | MEN1 (0.49) | ALDH1A1L3MBTL1MEN1KMT2A | |
| SCHEMBL21900646 | 0.74 | SCN4A (0.52) | SCN4ASCN8ALMNASCN1ASCN5A | |
| SCHEMBL8622906 | 0.74 | HTT (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0492615-B1 | Process for producing biguanide derivative | IDEMITSU KOSAN CO (JP) | 1995-03-08 | — | — | EP | disclosed |
| US-5286905-A | Heating hydrogen halide salt of phenoxyalkylamine with dicyandiamide in paraffinic hydrocarbon solvent | IDEMITSU KOSAN COMPANY LIMITED (JP) | 1994-02-15 | — | — | US | disclosed |
| EP-0492615-A1 | Process for producing biguanide derivative | IDEMITSU KOSAN COMPANY LIMITED (JP) | 1992-07-01 | — | — | EP | disclosed |