Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.65 |
| ▸ | MEN1 | O00255 | 3/20 | 0.65 |
| ▸ | F10 | P00742 | 2/20 | 0.60 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.54 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.54 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.54 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.54 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.54 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.54 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.54 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.54 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.54 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.54 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | NPC1 | O15118 | 4/20 | 0.52 |
| ▸ | RAB9A | P51151 | 4/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | SNCA | P37840 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9126018 | 0.92 | KMT2A (0.64) | KMT2AMEN1F10HDAC1HDAC3 | |
| SCHEMBL9124828 | 0.89 | MEN1 (0.62) | KMT2AMEN1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL9125948 | 0.88 | F10 (0.63) | KMT2AMEN1F10HDAC1HDAC3 | |
| SCHEMBL9124660 | 0.88 | KMT2A (0.55) | KMT2AMEN1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL9124786 | 0.85 | KMT2A (0.58) | KMT2AMEN1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL9124818 | 0.84 | TSHR (0.53) | KMT2AMEN1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL9128477 | 0.82 | KMT2A (0.55) | KMT2AMEN1HDAC1HDAC3HDAC2 | |
| SCHEMBL9128668 | 0.82 | MEN1 (0.48) | KMT2AMEN1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL9126538 | 0.79 | MAPT (0.52) | KMT2AMEN1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL9126492 | 0.79 | KMT2A (0.48) | KMT2AMEN1SMN1; SMN2ALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5413997-A | For treatment of osteoporosis | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1995-05-09 | — | — | US | disclosed |
| EP-0395093-B1 | TRIPHENYLMETHANE DERIVATIVES | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1993-09-01 | — | — | EP | disclosed |
| US-5112867-A | Osteoporosis Treatment | KYOWA HAKKO GOGYO CO., LTD. (JP) | 1992-05-12 | — | — | US | disclosed |
| EP-0395093-A1 | Triphenylmethane derivatives | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1990-10-31 | — | — | EP | disclosed |