Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 8/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.57 |
| ▸ | HPGD | P15428 | 6/20 | 0.51 |
| ▸ | TP53 | P04637 | 2/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 7/20 | 0.48 |
| ▸ | NPC1 | O15118 | 6/20 | 0.48 |
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | CASP1 | P29466 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.48 |
| ▸ | ESR1 | P03372 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.46 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.46 |
| ▸ | KDR | P35968 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10447891 | 0.94 | SMN1; SMN2 (0.63) | SMN1; SMN2ALDH1A1MAPK1HPGDTP53 | |
| SCHEMBL9126064 | 0.92 | SMN1; SMN2 (0.59) | SMN1; SMN2ALDH1A1MAPK1HPGDTP53 | |
| SCHEMBL9125869 | 0.89 | NPC1 (0.53) | SMN1; SMN2ALDH1A1MAPK1HPGDTP53 | |
| SCHEMBL9126606 | 0.89 | NPC1 (0.53) | SMN1; SMN2ALDH1A1MAPK1HPGDTP53 | |
| SCHEMBL9127262 | 0.87 | SMN1; SMN2 (0.47) | SMN1; SMN2ALDH1A1MAPK1HPGDTP53 | |
| SCHEMBL9125836 | 0.87 | SMN1; SMN2 (0.51) | SMN1; SMN2ALDH1A1MAPK1HPGDTP53 | |
| SCHEMBL9127236 | 0.87 | HPGD (0.57) | SMN1; SMN2ALDH1A1MAPK1HPGDKMT2A | |
| SCHEMBL9125044 | 0.85 | SMN1; SMN2 (0.46) | SMN1; SMN2ALDH1A1MAPK1HPGDTP53 | |
| SCHEMBL9126581 | 0.85 | NPC1 (0.49) | SMN1; SMN2ALDH1A1MAPK1HPGDTP53 | |
| SCHEMBL9126223 | 0.85 | SMN1; SMN2 (0.45) | SMN1; SMN2ALDH1A1MAPK1HPGDTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0524419-B1 | Heat-sensitive recording materials and phenol compounds | MITSUI TOATSU CHEMICALS (JP) | 1995-09-06 | — | — | EP | disclosed |
| US-5391806-A | A storage stable chromogens as color-developing agent or stabilizers | MITSUI TOATSU CHEMICALS, INCORPORATED (JP) | 1995-02-21 | — | — | US | disclosed |
| US-5270281-A | Chromogenic compound | MITSUI TOATSU CHEMICALS, INCORPORATED (JP) | 1993-12-14 | — | — | US | disclosed |
| EP-0524419-A1 | Heat-sensitive recording materials and phenol compounds | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1993-01-27 | — | — | EP | disclosed |