Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 10/20 | 0.55 |
| ▸ | CYP11B2 | P19099 | 10/20 | 0.55 |
| ▸ | CYP19A1 | P11511 | 5/20 | 0.54 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.40 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | FNTA | P49354 | 1/20 | 0.37 |
| ▸ | FNTB | P49356 | 1/20 | 0.37 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.37 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9120038 | 1.00 | CYP11B1 (0.55) | CYP11B1CYP11B2CYP19A1HSP90AA1HSP90AB1 | |
| SCHEMBL9119905 | 0.90 | CYP11B1 (0.59) | CYP11B1CYP11B2CYP19A1HSP90AA1HSP90AB1 | |
| SCHEMBL9121283 | 0.89 | CYP11B1 (0.68) | CYP11B1CYP11B2CYP19A1HSP90AA1HSP90AB1 | |
| Hydrochloric Acid SCHEMBL9122455 | 0.88 | CYP11B1 (0.66) | CYP11B1CYP11B2CYP19A1HSP90AA1HSP90AB1 | |
| SCHEMBL9123214 | 0.85 | CYP11B1 (0.66) | CYP11B1CYP11B2CYP19A1HSP90AA1HSP90AB1 | |
| SCHEMBL9121602 | 0.84 | CYP11B1 (0.57) | CYP11B1CYP11B2CYP19A1HSP90AA1HSP90AB1 | |
| SCHEMBL9122871 | 0.83 | CYP11B1 (0.56) | CYP11B1CYP11B2CYP19A1HSP90AA1HSP90AB1 | |
| SCHEMBL9122057 | 0.82 | CYP11B1 (0.60) | CYP11B1CYP11B2CYP19A1IDO1 | |
| SCHEMBL9640809 | 0.82 | CYP11B1 (0.54) | CYP11B1CYP11B2CYP19A1HSP90AA1HSP90AB1 | |
| SCHEMBL9121571 | 0.82 | CYP11B1 (0.62) | CYP11B1CYP11B2CYP19A1HSP90AA1HSP90AB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5439928-A | Enzyme inhibitors as antitumor agents for breast cancer | ORION-YHTYMA OY (FI) | 1995-08-08 | — | — | US | disclosed |