Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | SIRT2 | Q8IXJ6 | 7/20 | 0.35 |
| ▸ | SIRT1 | Q96EB6 | 4/20 | 0.35 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.35 |
| ▸ | BCHE | P06276 | 3/20 | 0.35 |
| ▸ | ACHE | P22303 | 3/20 | 0.35 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.35 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.35 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.35 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.35 |
| ▸ | SELP | P16109 | 3/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | PGR | P06401 | 1/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.33 |
| ▸ | AR | P10275 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9126739 | 0.92 | MEN1 (0.42) | MEN1ALDH1A1HPGDKMT2ASIRT2 | |
| SCHEMBL9126181 | 0.92 | MEN1 (0.42) | MEN1ALDH1A1HPGDKMT2ASIRT2 | |
| SCHEMBL9125725 | 0.92 | MEN1 (0.42) | MEN1ALDH1A1HPGDKMT2ASIRT2 | |
| SCHEMBL9125656 | 0.92 | MEN1 (0.42) | MEN1ALDH1A1HPGDKMT2ASIRT2 | |
| SCHEMBL9126692 | 0.91 | BCHE (0.38) | MEN1ALDH1A1HPGDKMT2ASIRT2 | |
| SCHEMBL9126453 | 0.91 | MEN1 (0.40) | MEN1ALDH1A1HPGDKMT2ASIRT2 | |
| SCHEMBL9127439 | 0.88 | TLR2 (0.41) | MEN1ALDH1A1HPGDKMT2ASIRT2 | |
| SCHEMBL9128727 | 0.88 | TLR2 (0.41) | MEN1ALDH1A1HPGDKMT2ASIRT2 | |
| SCHEMBL9127067 | 0.86 | TLR4 (0.41) | MEN1ALDH1A1HPGDKMT2ASELP | |
| SCHEMBL9126017 | 0.86 | TLR4 (0.41) | MEN1ALDH1A1HPGDKMT2ASELP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5432267-A | Inhibits tumor necrosis factor derivation by endotoxin | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 1995-07-11 | — | — | US | disclosed |
| EP-0563908-A1 | Amino sugar derivatives | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 1993-10-06 | — | — | EP | disclosed |