SCHEMBL9124256

SCHEMBL9124256

O=C(Nc1ccccc1)Oc1ccccc1-c1ccccc1O

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 4/20 0.54
GAA P10253 3/20 0.54
KDM4E B2RXH2 2/20 0.54
BLM P54132 1/20 0.54
HSP90AA1 P07900 1/20 0.50
FABP7 O15540 1/20 0.49
FABP3 P05413 1/20 0.49
FABP5 Q01469 1/20 0.49
ALDH1A1 P00352 4/20 0.48
FAAH O00519 1/20 0.48
SMN1; SMN2 Q16637 2/20 0.47
HTT P42858 2/20 0.47
ATM Q13315 1/20 0.47
MEN1 O00255 2/20 0.46
MAPT P10636 2/20 0.46
TP53 P04637 2/20 0.46
EPHX1 P07099 1/20 0.46
TSHR P16473 1/20 0.46
EPHX2 P34913 1/20 0.46
CDK9 P50750 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9129060 0.85 HSP90AA1 (0.46) KMT2AGAAKDM4EBLMHSP90AA1
SCHEMBL1835068 0.83 GAA (0.56) KMT2AGAAKDM4EBLMHSP90AA1
SCHEMBL3309694 0.79 FABP7 (0.56) KMT2AGAAKDM4EFABP7FABP3
SCHEMBL9129065 0.79 PTGS1 (0.46) KMT2AGAAKDM4EBLMHSP90AA1
SCHEMBL9126088 0.78 KMT2A (0.43) KMT2AGAAKDM4EBLMHSP90AA1
SCHEMBL7495369 0.77 TP53 (0.50) KMT2AGAAKDM4EBLMHSP90AA1
SCHEMBL16236569 0.77 FABP7 (0.54) KMT2AGAAKDM4EBLMFABP7
SCHEMBL9126097 0.77 KMT2A (0.41) KMT2AGAAKDM4EBLMHSP90AA1
SCHEMBL9127054 0.75 ATM (0.54) KMT2AALDH1A1FAAHSMN1; SMN2ATM
SCHEMBL24282083 0.75 KDM4E (0.59) KMT2AGAAKDM4EBLMHSP90AA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0524419-B1 Heat-sensitive recording materials and phenol compounds MITSUI TOATSU CHEMICALS (JP) 1995-09-06 EP disclosed
US-5391806-A A storage stable chromogens as color-developing agent or stabilizers MITSUI TOATSU CHEMICALS, INCORPORATED (JP) 1995-02-21 US disclosed
US-5270281-A Chromogenic compound MITSUI TOATSU CHEMICALS, INCORPORATED (JP) 1993-12-14 US disclosed
EP-0524419-A1 Heat-sensitive recording materials and phenol compounds MITSUI TOATSU CHEMICALS, Inc. (JP) 1993-01-27 EP disclosed