Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPIA | P62937 | 12/20 | 0.61 |
| ▸ | PPIF | P30405 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9122377 | 0.90 | PPIA (0.60) | PPIARAB9AMAPTSMN1; SMN2MEN1 | |
| SCHEMBL9124394 | 0.90 | PPIA (0.68) | PPIAPPIFMEN1KMT2A | |
| SCHEMBL9126145 | 0.90 | PPIA (0.75) | PPIAPPIFMAPTMEN1KMT2A | |
| SCHEMBL9122331 | 0.87 | PPIA (0.61) | PPIAPPIFRAB9AMAPTSMN1; SMN2 | |
| SCHEMBL9126357 | 0.85 | PPIA (0.51) | PPIAPPIFRAB9AMAPTSMN1; SMN2 | |
| SCHEMBL9126340 | 0.83 | PPIA (0.54) | PPIARAB9AMAPTSMN1; SMN2MEN1 | |
| SCHEMBL9124740 | 0.82 | PPIA (0.55) | PPIARAB9AMAPTSMN1; SMN2MEN1 | |
| SCHEMBL9123692 | 0.81 | PPIA (0.49) | PPIAPPIFRAB9AMAPTSMN1; SMN2 | |
| SCHEMBL9126341 | 0.81 | PPIA (0.56) | PPIARAB9AMAPTSMN1; SMN2MEN1 | |
| SCHEMBL9125099 | 0.81 | PPIA (0.72) | PPIAPPIFMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5409943-A | [(alkoxy)pyridinyl]amine compounds which are useful in the treatment of gastrointestinal disorders | SMITHKLINE BEECHAM INTERCREDIT B.V. (NL) | 1995-04-25 | — | — | US | disclosed |