Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR4 | O00206 | 11/20 | 0.43 |
| ▸ | SSTR2 | P30874 | 2/20 | 0.38 |
| ▸ | SSTR3 | P32745 | 2/20 | 0.38 |
| ▸ | SSTR5 | P35346 | 2/20 | 0.38 |
| ▸ | LY96 | Q9Y6Y9 | 6/20 | 0.38 |
| ▸ | SYNJ2 | O15056 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ABL1 | P00519 | 1/20 | 0.37 |
| ▸ | ALPL | P05186 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | ALPI | P09923 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | ALPG | P10696 | 1/20 | 0.37 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | GALK1 | P51570 | 1/20 | 0.37 |
| ▸ | CASP7 | P55210 | 1/20 | 0.37 |
| ▸ | CASP6 | P55212 | 1/20 | 0.37 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9125721 | 1.00 | TLR4 (0.43) | TLR4SSTR2SSTR3SSTR5LY96 | |
| SCHEMBL9127440 | 0.95 | TLR4 (0.43) | TLR4SSTR2SSTR3SSTR5LY96 | |
| SCHEMBL9127443 | 0.95 | TLR4 (0.43) | TLR4SSTR2SSTR3SSTR5LY96 | |
| SCHEMBL9126740 | 0.92 | TLR4 (0.50) | TLR4LY96SELP | |
| SCHEMBL9128952 | 0.92 | TLR4 (0.50) | TLR4LY96SELP | |
| SCHEMBL9129908 | 0.92 | TLR4 (0.50) | TLR4LY96SELP | |
| SCHEMBL9128948 | 0.92 | TLR4 (0.50) | TLR4LY96SELP | |
| SCHEMBL9129913 | 0.92 | TLR4 (0.50) | TLR4LY96SELP | |
| SCHEMBL9568238 | 0.92 | TLR4 (0.42) | TLR4LY96 | |
| SCHEMBL9125046 | 0.92 | TLR4 (0.42) | TLR4LY96 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5432267-A | Inhibits tumor necrosis factor derivation by endotoxin | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 1995-07-11 | — | — | US | disclosed |
| EP-0563908-A1 | Amino sugar derivatives | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 1993-10-06 | — | — | EP | disclosed |