Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERCC1 | P07992 | 1/20 | 0.52 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.51 |
| ▸ | EPHX2 | P34913 | 4/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | SLC13A5 | Q86YT5 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2635463 | 0.91 | ERCC1 (0.55) | ERCC1ERCC4ALDH1A1HPGDKDM4E | |
| SCHEMBL1750644 | 0.90 | ERCC1 (0.54) | ERCC1ERCC4ALDH1A1HPGDKDM4E | |
| SCHEMBL2635819 | 0.89 | EPHX2 (0.50) | ERCC1ERCC4ALDH1A1HPGDKDM4E | |
| SCHEMBL2635473 | 0.88 | EPHX2 (0.51) | ERCC1ERCC4ALDH1A1HPGDKDM4E | |
| Hydrochloric Acid SCHEMBL4682675 | 0.87 | EPHX2 (0.50) | ERCC1ERCC4ALDH1A1HPGDKDM4E | |
| SCHEMBL3081025 | 0.87 | EPHX2 (0.47) | ERCC1ERCC4ALDH1A1HPGDKDM4E | |
| SCHEMBL3093689 | 0.86 | EPHX2 (0.49) | ERCC1ERCC4ALDH1A1HPGDKDM4E | |
| SCHEMBL30791545 | 0.85 | EPHX2 (0.61) | ERCC1ERCC4ALDH1A1HPGDKDM4E | |
| SCHEMBL1751194 | 0.85 | ERCC1 (0.49) | ERCC1ERCC4ALDH1A1HPGDKDM4E | |
| SCHEMBL14782772 | 0.83 | ERCC1 (0.52) | ERCC1ERCC4ALDH1A1HPGDKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8129538-B1 | Renin inhibitors | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2012-03-06 | — | — | US | disclosed |